The Falling Incidence of Hematologic Cancer After Heart Transplantation
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The Falling Incidence of Hematologic Cancer After Heart TransplantationAuthor(s)
Date
2014-10-01Citation
Crespo-Leiro MG, Delgado-Jiménez J, López L. The falling incidence of hematologic cancer after heart transplantation. Clin Transplant. 2014;28:1142-1147
Abstract
[Abstract] Background. A number of changes in the management of heart transplantation (HT) patients have each tended to reduce the risk of post-HT hematologic cancer, but little information is available concerning the overall effect on incidence in the HT population.
Methods. Comparison of data from the Spanish Post-Heart-Transplantation Tumour Registry for the periods 1991–2000 and 2001–2010.
Results. The incidence among patients who underwent HT in the latter period was about half that observed in the former, with a particularly marked improvement in regard to incidence more than five yr post-HT.
Conclusions. Changes in HT patient management have jointly reduced the risk of hematologic cancer in the Spanish HT population. Long-term risk appears to have benefited more than short-term risk.
Keywords
Cancer incidence
Heart transplantation
Immunodepressive therapy
Long-term complications
Lymphomas
Mortality
Heart transplantation
Immunodepressive therapy
Long-term complications
Lymphomas
Mortality
Editor version
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This is the peer reviewed version of the following article which has been published in final form at Wiley Online Library. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for self-archiving