Browsing by Author "Vizoso-Vázquez, Ángel"
Now showing items 1-14 of 14
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Adaptación de la docencia práctica de materias de Bioquímica en tiempos de la pandemia por el Covid-19
Vizoso-Vázquez, Ángel; Rodríguez_Torres, Ana M.; Freire-Picos, María Ángeles (Universidade da Coruña, Servizo de Publicacións, 2021)[Resumen] En este trabajo se comentan los retos que nos vimos obligados a afrontar y las soluciones tomadas por el profesorado a fin de adaptar la docencia de prácticas de laboratorio a la situación de pandemia causada por ... -
Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications
Barreiro-Alonso, Aida; Cámara-Quílez, María; Salamini-Montemurri, Martín; Lamas, Mónica; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Martínez-Iglesias, Olaia; Figueroa, Angélica; Cerdán, María Esperanza (MDPI, 2019-11-05)[Abstract] High mobility group box B (HMGB) proteins are pivotal in the development of cancer. Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement of HMGB proteins and their interactome ... -
HMG Proteins from Molecules to Disease [Editorial]
Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2022-02-17) -
Identification of lncRNAs Deregulated in Epithelial Ovarian Cancer Based on a Gene Expression Profiling Meta-Analysis
Salamini-Montemurri, Martín; Lamas, Mónica; Lorenzo-Catoira, Lidia; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2023-06-28)[Abstract] Epithelial ovarian cancer (EOC) is one of the deadliest gynecological cancers worldwide, mainly because of its initially asymptomatic nature and consequently late diagnosis. Long non-coding RNAs (lncRNA) are ... -
Ixr1 Regulates Ribosomal Gene Transcription and Yeast Response to Cisplatin
Vizoso-Vázquez, Ángel; Lamas, Mónica; González-Siso, María-Isabel; Cerdán, María Esperanza (Springer Nature, 2018-02-15)[Abstract] Ixr1 is a Saccharomyces cerevisiae HMGB protein that regulates the hypoxic regulon and also controls the expression of other genes involved in the oxidative stress response or re-adaptation of catabolic and ... -
Mechanisms of transcriptional regulation mediated by "IXR1" in yeast
Vizoso-Vázquez, Ángel (2015)[Resumen] Ixrl es una proteína de Saccharomyces cerevisiae previamente relacionada con la respuesta a hipoxia y a estrés oxidativo, así como en la resistencia a cisplatino. El trabajo presentado en esta Tesis permite ... -
O programa STEmbach na Área de Bioquímica e Bioloxía Molecular da Facultade de Ciencias
Lamas, Mónica; Lourido Salas, Lucía María; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Vizoso-Vázquez, Ángel (Centro Universitario de Formación e Innovación Educativa (CUFIE), Universidade da Coruña, 2022)[Resumo] O programa do bacharelato de excelencia en Ciencias e Tecnoloxía, STEMbach, é un programa da Xunta de Galicia, orientado a alumnos de primeiro e segundo de Bacharelato cuxo obxetivo é fomentar as ciencias entre ... -
Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin
Rodríguez Lombardero, Silvia; Rodríguez-Belmonte, Esther; González-Siso, María-Isabel; Vizoso-Vázquez, Ángel; Valdiglesias, Vanessa; Laffon, Blanca; Cerdán, María Esperanza (Multidisciplinary Digital Publishing Institute, 2014)[Abstract] Sky1 is the only member of the SR (Serine–Arginine) protein kinase family in Saccharomyces cerevisiae. When yeast cells are treated with the anti-cancer drug cisplatin, Sky1 kinase activity is necessary to produce ... -
Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
Alarcón-Veleiro, Carmen; Mato-Basalo, Rocío; Lucio-Gallego, Sergio; Vidal-Pampín, Andrea; Quindós-Varela, María; Al-Qatarneh, Thamer; Berrecoso, Germán; Vizoso-Vázquez, Ángel; Arufe, M.C.; Fafián Labora, Juan Antonio (MDPI, 2023-01-12)[Abstract] Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. The current treatment for EOC involves surgical debulking of the tumors followed by a combination of chemotherapy. While most patients ... -
Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer [Review]
Lamas, Mónica; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Cámara-Quílez, M.; Cerdán, María Esperanza (MDPI, 2023-04-11)[Abstract] Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of ... -
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use
Salamini-Montemurri, Martín; Lamas, Mónica; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2020-04-21)[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor. In this review we aim to highlight ... -
The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer
Salamini-Montemurri, Martín; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Lorenzo-Catoira, Lidia; Rodríguez-Belmonte, Esther; Cerdán, María Esperanza; Lamas, Mónica (MDPI, 2024-03-07)[Abstract] Human high-mobility group-B (HMGB) proteins regulate gene expression in prostate cancer (PCa), a leading cause of oncological death in men. Their role in aggressive PCa cancers, which do not respond to hormonal ... -
The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis
Rico Díaz, Agustín; Barreiro-Alonso, Aida; Rey-Souto, Cora; Becerra, Manuel; Lamas, Mónica; Cerdán, María Esperanza; Vizoso-Vázquez, Ángel (MDPI, 2021-08-21)[Abstract] In the traditional fermentative model yeast Saccharomyces cerevisiae, ScIxr1 is an HMGB (High Mobility Group box B) protein that has been considered as an important regulator of gene transcription in response ... -
The HMGB1-2 Ovarian Cancer Interactome: the Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response
Cámara-Quílez, María; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2020-08-27)[Abstract] High mobility group box B (HMGB) proteins are overexpressed in different types of cancers such as epithelial ovarian cancers (EOC). We have determined the first interactome of HMGB1 and HMGB2 in epithelial ovarian ...