Browsing by Author "Rodríguez-Belmonte, Esther"
Now showing items 1-13 of 13
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Cellulases from thermophiles found by metagenomics
Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Cerdán, María Esperanza; Rodríguez-Belmonte, Esther; Becerra, Manuel; González-Siso, María-Isabel (MDPI, 2018-07-10)[Abstract] Cellulases are a heterogeneous group of enzymes that synergistically catalyze the hydrolysis of cellulose, the major component of plant biomass. Such reaction has biotechnological applications in a broad spectrum ... -
Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications
Barreiro-Alonso, Aida; Cámara-Quílez, M.; Salamini-Montemurri, Martín; Lamas, Mónica; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Martínez-Iglesias, Olaia; Figueroa, Angélica; Cerdán, María Esperanza (MDPI, 2019-11-05)[Abstract] High mobility group box B (HMGB) proteins are pivotal in the development of cancer. Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement of HMGB proteins and their interactome ... -
Comparative Metagenomic Analysis of Two Hot Springs From Ourense (Northwestern Spain) and Others Worldwide
De Castro de Antonio, María Eugenia; Escuder-Rodríguez, Juan-José; Becerra, Manuel; Rodríguez-Belmonte, Esther; González-Siso, María-Isabel (Frontiers, 2021-11-26)[Abstract] With their circumneutral pH and their moderate temperature (66 and 68°C, respectively), As Burgas and Muiño da Veiga are two important human-use hot springs, previously studied with traditional culture methods, ... -
Delineating the HMGB1 and HMGB2 Interactome in Prostate and Ovary Epithelial Cells and Its Relationship With Cancer
Barreiro-Alonso, Aida; Lamas, Mónica; García Díaz, Rosa; Rodríguez-Belmonte, Esther; Yu, Lu; Pardo, Mercedes; Choudhary, Jyoti; Cerdán, María Esperanza (Impact Journals, 2018-04-10)[Abstract] High Mobility Group B (HMGB) proteins are involved in cancer progression and in cellular responses to platinum compounds used in the chemotherapy of prostate and ovary cancer. Here we use affinity purification ... -
Differential Characteristics of HMGB2 Versus HMGB1 and their Perspectives in Ovary and Prostate Cancer
Cámara-Quílez, M.; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza; Lamas, Mónica (Bentham Science, 2020)[Abstract] We have summarized common and differential functions of HMGB1 and HMGB2 proteins with reference to pathological processes, with a special focus on cancer. Currently, several “omic” approaches help us compare the ... -
Estudio de los genes KIPDCB y KIGSK-3 de la levadura "Kluyveromyces lactis"
Rodríguez-Belmonte, Esther (1997)[Resumen] En el presente trabajo se ha secuenciado una región de 5kb de DNA del cromosoma seis de la levadura Kluyveromyces Lactis, en la que se han identificado dos pautas de lectura abierta, las cuales se han subclonado ... -
Exploring the Taxonomical and Functional Profile of As Burgas Hot Spring Focusing On Thermostable β-galactosidases
De Castro de Antonio, María Eugenia; Doane, Michael P.; Dinsdale, Elizabeth Ann; Rodríguez-Belmonte, Esther; González-Siso, María-Isabel (Springer Nature, 2021-01-08)[Abstract] In the present study we investigate the microbial community inhabiting As Burgas geothermal spring, located in Ourense (Galicia, Spain). The approximately 23 Gbp of Illumina sequences generated for each replicate ... -
Identification of lncRNAs Deregulated in Epithelial Ovarian Cancer Based on a Gene Expression Profiling Meta-Analysis
Salamini-Montemurri, Martín; Lamas, Mónica; Lorenzo-Catoira, Lidia; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2023-06-28)[Abstract] Epithelial ovarian cancer (EOC) is one of the deadliest gynecological cancers worldwide, mainly because of its initially asymptomatic nature and consequently late diagnosis. Long non-coding RNAs (lncRNA) are ... -
O programa STEmbach na Área de Bioquímica e Bioloxía Molecular da Facultade de Ciencias
Lamas, Mónica; Lourido Salas, Lucía María; Barreiro-Alonso, Aida; Rodríguez-Belmonte, Esther; Vizoso-Vázquez, Ángel (Centro Universitario de Formación e Innovación Educativa (CUFIE), Universidade da Coruña, 2022)[Resumo] O programa do bacharelato de excelencia en Ciencias e Tecnoloxía, STEMbach, é un programa da Xunta de Galicia, orientado a alumnos de primeiro e segundo de Bacharelato cuxo obxetivo é fomentar as ciencias entre ... -
Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin
Rodríguez Lombardero, Silvia; Rodríguez-Belmonte, Esther; González-Siso, María-Isabel; Vizoso-Vázquez, Ángel; Valdiglesias, Vanessa; Laffon, Blanca; Cerdán, María Esperanza (Multidisciplinary Digital Publishing Institute, 2014)[Abstract] Sky1 is the only member of the SR (Serine–Arginine) protein kinase family in Saccharomyces cerevisiae. When yeast cells are treated with the anti-cancer drug cisplatin, Sky1 kinase activity is necessary to produce ... -
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use
Salamini-Montemurri, Martín; Lamas, Mónica; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2020-04-21)[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor. In this review we aim to highlight ... -
The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer
Salamini-Montemurri, Martín; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Lorenzo-Catoira, Lidia; Rodríguez-Belmonte, Esther; Cerdán, María Esperanza; Lamas, Mónica (MDPI, 2024-03-07)[Abstract] Human high-mobility group-B (HMGB) proteins regulate gene expression in prostate cancer (PCa), a leading cause of oncological death in men. Their role in aggressive PCa cancers, which do not respond to hormonal ... -
The HMGB1-2 Ovarian Cancer Interactome: the Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response
Cámara-Quílez, M.; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2020-08-27)[Abstract] High mobility group box B (HMGB) proteins are overexpressed in different types of cancers such as epithelial ovarian cancers (EOC). We have determined the first interactome of HMGB1 and HMGB2 in epithelial ovarian ...