Now showing items 1-14 of 14

    • A data mining approach for classification of orthostatic and essential tremor based on MRI‐derived brain volume and cortical thickness 

      Benito-León, Julián; Louis, Elan D.; Mato-Abad, Virginia; Sánchez‐Ferro, Alvaro; Romero, Juan Pablo; Matarazzo, Michele; Serrano, J. Ignacio (John Wiley & Sons Ltd., 2019-11-26)
      [Abstract] Objective - Orthostatic tremor (OT) is an extremely rare, misdiagnosed, and underdiagnosed disorder affecting adults in midlife. There is debate as to whether it is a different condition or a variant of essential ...
    • Application for Decision-Making on Mild Cognitive Impairments 

      González-Martín, Erick; Alvarellos, Alberto; Mato-Abad, Virginia; Pías-Peleteiro, Juan M.; Jiménez Martín, Isabel; Cedrón, Francisco (MDPI, 2021)
      [Abstract] Life expectancy in Western countries is increasing. The fact that humans are living longer lives presents new challenges to people’s quality of life. Some of the problems that most affect older people are the ...
    • ASAP (Automatic Software for ASL Processing): A toolbox for processing Arterial Spin Labeling images 

      Mato-Abad, Virginia; García-Polo, Pablo; O’Daly, Owen; Hernández-Tamames, Juan Antonio; Zelaya, Fernando (2016)
      [Abstract]: The method of Arterial Spin Labeling (ASL) has experienced a significant rise in its application to functional imaging, since it is the only technique capable of measuring blood perfusion in a truly non-invasive ...
    • Classification of mild cognitive impairment and Alzheimer’s Disease with machine-learning techniques using 1H Magnetic Resonance Spectroscopy data 

      Munteanu, Cristian-Robert; Fernández-Lozano, Carlos; Mato-Abad, Virginia; Pita-Fernández, Salvador; Álvarez-Linera, Juan; Hernández-Tamames, Juan Antonio; Pazos, A. (Elsevier, 2015-03-30)
      [Abstract] Several magnetic resonance techniques have been proposed as non-invasive imaging biomarkers for the evaluation of disease progression and early diagnosis of Alzheimer’s Disease (AD). This work is the first ...
    • Classification of Radiologically Isolated Syndrome and Clinically Isolated Syndrome with Machine-Learning Techniques 

      Mato-Abad, Virginia; Labiano-Fontcuberta, Andrés; Rodríguez-Yáñez, Santiago; García-Vázquez, Rafael; Munteanu, Cristian-Robert; Andrade-Garda, Javier; Domingo-Santos, Ángela; Galán Sánchez-Seco, Victoria; Aladro, Yolanda; Martínez-Ginés, Mª Luisa; Ayuso, Lucía; Benito-León, Julián (2019)
      [Abstract]: Introduction: The unanticipated magnetic resonance imaging (MRI) detection in the brain of asymptomatic subjects of white matter lesions suggestive of multiple sclerosis (MS) has been named as radiologically ...
    • Diffusion tensor imaging in orthostatic tremor: a tract‐based spatial statistics study 

      Benito-León, Julián; Romero, Juan Pablo; Louis, Elan D.; Sánchez‐Ferro, Alvaro; Matarazzo, Michele; Molina‐Arjona, José A.; Mato-Abad, Virginia (John Wiley & Sons Ltd., 2019-10-06)
      [Abstract] Objective The pathogenesis of orthostatic tremor (OT) is unknown. We investigated OT‐related white matter changes and their correlations with scores from a neuropsychological testing battery. Methods Diffusion ...
    • Effect of water T2 shortening in the quantification of in-vitro proton MR spectroscopy 

      Hernández-Tamames, Juan Antonio; Mato-Abad, Virginia; García-Álvarez, Roberto; González-Zabaleta, Javier; Pereira-Loureiro, Javier; Álvarez-Linera, Juan (Wiley, 2015-05-21)
      [Abstract] PURPOSE. This work studies the relationship between in-vitro Proton Magnetic Resonance Spectroscopy metabolite quantification and water T2 decay. MATERIALS AND METHODS. An in-vitro correspondence is established ...
    • Environmental Sustainability in Information Technologies Governance 

      Rivas-Asanza, Wilmer; Celleri-Pacheco, Jennifer; Andrade-Garda, Javier; García-Vázquez, Rafael; Rodríguez-Yáñez, Santiago; Mato-Abad, Virginia; Suárez-Garaboa, Sonia (M D P I AG, 2018-12-15)
      [Abstract] In the present day, many risk factors affect the continuity of a business. However, this situation produces a conducive atmosphere to approach alternatives that relieve this situation for organizations. Within ...
    • Random Forest-Based Prediction of Stroke Outcome 

      Fernández-Lozano, Carlos; Hervella, Pablo; Mato-Abad, Virginia; Rodríguez-Yáñez, Manuel; Suárez-Garaboa, Sonia; López Dequidt, Iria Alejandra; Estany-Gestal, Ana; Sobrino, Tomás; Campos, Francisco; Castillo, José; Rodríguez-Yáñez, Santiago; Iglesias Rey, Ramón (Nature Research, 2021)
      [Abstract] We research into the clinical, biochemical and neuroimaging factors associated with the outcome of stroke patients to generate a predictive model using machine learning techniques for prediction of mortality and ...
    • Senolytic Activity of Small Molecular Polyphenols from Olive Restores Chondrocyte Redifferentiation and Promotes a Pro-Regenerative Environment in Osteoarthritis 

      Varela-Eirín, Marta; Carpintero-Fernández, Paula; Sánchez Temprano, Agustín; Varela Vázquez, Adrián; Luis Paíno, Carlos; Casado-Díaz, Antonio; Calañas Continente, Alfonso; Mato-Abad, Virginia; Fonseca, Eduardo; Kandouz, Mustapha; Blanco, Alfonso; Caeiro, José Ramón; Mayan, Maria D. (Impact Journals LLC, 2020-08-03)
      [Abstract] Articular cartilage and synovial tissue from patients with osteoarthritis (OA) show an overactivity of connexin43 (Cx43) and accumulation of senescent cells associated with disrupted tissue regeneration and ...
    • Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis 

      Varela-Eirín, Marta; Varela Vázquez, Adrián; Guitián-Caamaño, Amanda; Luis Paíno, Carlos; Mato-Abad, Virginia; Largo, Raquel; Aasen, Trond; Tabernero, Arantxa; Fonseca, Eduardo; Kandouz, Mustapha; Caeiro, José Ramón; Blanco, Alfonso; Mayan, Maria D. (Nature Publishing Group, 2018-12-05)
      [Abstract] Osteoarthritis (OA), a chronic disease characterized by articular cartilage degeneration, is a leading cause of disability and pain worldwide. In OA, chondrocytes in cartilage undergo phenotypic changes and ...
    • The partial volume effect in the quantification of 1H magnetic resonance spectroscopy in Alzheimer's disease and aging 

      Mato-Abad, Virginia; Quirós, Alicia; García-Álvarez, Roberto; Pereira-Loureiro, Javier; Álvarez-Linera, Juan; Frank, Ana; Hernández-Tamames, Juan Antonio (IOS Press, 2014)
      [Abstract] 1H-MRS variability increases due to normal aging and also as a result of atrophy in grey and white matter caused by neurodegeneration. In this work, an automatic process was developed to integrate data from ...
    • Using Artificial Neural Networks for Identifying Patients with Mild Cognitive Impairment Associated with Depression Using Neuropsychological Test Features 

      Mato-Abad, Virginia; Jiménez, Isabel; García-Vázquez, Rafael; Aldrey, José M.; Rivero, Daniel; Cacabelos, Purificación; Andrade-Garda, Javier; Pías-Peleteiro, Juan M.; Rodríguez-Yáñez, Santiago (M D P I AG, 2018-09-12)
      [Abstract] Depression and cognitive impairment are intimately associated, especially in elderly people. However, the association between late-life depression (LLD) and mild cognitive impairment (MCI) is complex and currently ...
    • White matter microstructural changes are related to cognitive dysfunction in essential tremor 

      Benito-León, Julián; Mato-Abad, Virginia; Louis, Elan D.; Hernández-Tamames, Juan Antonio; Álvarez-Linera, Juan; Bermejo-Pareja, Félix; Domingo-Santos, Ángela; Collado, Luis; Romero, Juan Pablo (Nature Research, 2017-06-07)
      [Abstract]: Diffusion tensor imaging (DTI) studies have detected white matter microstructural changes in essential tremor (ET). However, it is still unclear whether these changes are related to cognitive deficits, which ...