Now showing items 1-7 of 7

    • Comparative Study on Effects of Two Different Types of Titanium Dioxide Nanoparticles on Human Neuronal Cells 

      Valdiglesias, Vanessa; Costa, C.; Sharma, Vyom; Kiliç, Gözde; Pásaro, Eduardo; Teixeira, João Paulo; Dhawan, Alok; Laffon, Blanca (Elsevier, 2013-04-15)
      [Abstract] Titanium dioxide (TiO2) are among most frequently used nanoparticles (NPs). They are present in a variety of consumer products, including food industry in which they are employed as an additive. The potential ...
    • Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors 

      Teixeira Gomes, Armanda; Laffon, Blanca; Valdiglesias, Vanessa; Gostner, Johanna; Felder, Thomas; Costa, C.; Madureira, Joana; Fuchs, Dietmar; Teixeira, João; Costa, Solange (2021)
      [Abstract] Ageing is accompanied with a decline in several physiological systems. Frailty is an age-related syndrome correlated to the loss of homeostasis and increased vulnerability to stressors, which is associated with ...
    • Genotoxicity of TiO2 Nanoparticles in Four Different Human Cell Lines (A549, HEPG2, A172 and SH-SY5Y) 

      Brandão, Fátima; Fernández‐Bertólez, Natalia; Rosário, Fernada; Bessa, Maria João; Fraga, Sónia; Pásaro, Eduardo; Teixeira, João; Laffon, Blanca; Valdiglesias, Vanessa; Costa, C. (2020)
      [Abstrac] Titanium dioxide nanoparticles (TiO2 NPs) have a wide variety of applications in many consumer products, including as food additives, increasing the concern about the possible hazards that TiO2 NPs may pose to ...
    • Neuronal Cytotoxicity and Genotoxicity Induced by Zinc Oxide Nanoparticles 

      Valdiglesias, Vanessa; Costa, C.; Kiliç, Gözde; Costa, Solange; Pásaro, Eduardo; Laffon, Blanca; Teixeira, João Paulo (Elsevier, 2013-03-26)
      [Abstract] Zinc oxide nanoparticles (ZnO NPs) are one of the most abundantly used nanomaterials in consumer products and biomedical applications. As a result, human exposure to these NPs is highly frequent and they have ...
    • Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage 

      Valdiglesias, Vanessa; Fernández-Bertólez, Natalia; Lema-Arranz, Carlota; Rodríguez-Fernández, Raquel; Pásaro, Eduardo; Reis, Ana Teresa; Teixeira, João; Costa, C.; Laffon, Blanca (MDPI, 2021-07-27)
      [Abstract] Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue ...
    • Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells 

      Fernández-Bertólez, Natalia; Brandão, Fátima; Costa, C.; Pásaro, Eduardo; Teixeira, João; Laffon, Blanca; Valdiglesias, Vanessa (2021)
      [Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) ...
    • The hCOMET Project: International Database Comparison of Results with the Comet Assay in Human Biomonitoring. Baseline Frequency of DNA Damage and Effect of Main Confounders 

      Milić, Mirta; Ceppi, Marcello; Bruzzone, Marco; Azqueta, Amaya; Brunborg, Gunnar; Godschalk, Roger; Koppen, Gudrun; Langie, Sabine; Møller, Peter; Alija, Avdulla; Anderson, Diana; Andreoli, Cristina; Asllani, Fisnik; Boutet-Robinet, Elisa; Buschini, Annamaria; Cavallo, Delia; Costa, Solange; Da Silva, Juliana; Del Boˊ, Cristian; Djelić, Ninoslav; Dobrzyńska, Malgorzata; Dvořáková, Monika; Gajski, Goran; Galati, Serena; García Lima, Omar; Giovannelli, Lisa; Goroshinskaya, Irina A.; Grindel, Annemarie; Hernández, Alba; Hernández, Carlos; Holven, Kirsten B.; Ibero-Baraibar, Idoia; Ottestad, Inger; Kadioglu, Ela; Kuznetsova, Elena; Ladeira, Carina; Laffon, Blanca; Lamonaca, Palma; Lebailly, Pierre; Louro, Henriqueta; Mandina Cardoso, Tania; Marcon, Francesca; Marcos, Ricard; Moretti, Massimo; Moretti, Silvia; Najafzadeh, Mojgan; Nemeth, Zsuzsanna; Neri, Monica; Novotna, Bozena; Orlow, Irene; Paduchova, Zuzana; Pastor, Susana; Perdry, Hervé; Spremo-Potparević, Biljana; Ramadhani, Dwi; Riso, Patrizia; Rohr, Paula; Rojas, Emilio; Rossner, Pavel; Sardas, Semra; Silva, Maria João; Sirota, Nikolay; Smolkova, Bozena; Staruchova, Marta; Stetina, Rudolf; Stopper, Helga; Ursini, Cinzia Lucia; Valdiglesias, Vanessa; Valverde, Mahara; Volkovova, Katarina; Wagner, Karl-Heinz; Živković, Lada; Dušinská, Maria; Collins, Andrew R.; Bonassi, Stefano; Teixeira, João; Andrade, Vanessa Moraes de; Bankoglu, Ezgi Eylül; Barančoková, Magdaléna; Pereira, Cristiana; Dimitrijević-Srećković, Vesna; Sáfár, Anna; Surikova, Ekaterina; Vodička, Pavel; Başaran, Nurşen; Costa, C.; Ďuračková, Zdeňka; Kažimírová, Alena; Gützkow, Kristine Bjerve; Ulven, Stine Marie (2021)
      [Abstract] The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification ...