Browsing by Author "Arntz, O.J."
Now showing items 1-3 of 3
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Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
Fafián Labora, Juan Antonio; Lesende-Rodríguez, Iván; Fernández-Pernas, Pablo; Sangiao-Alvarellos, Susana; Monserrat, Lorenzo; Arntz, O.J.; Van de Loo, F.J.; Mateos, Jesús; Arufe, M.C. (Nature, 2017-03-06)[Abstract] Stem cells possess significant age-dependent differences in their immune-response profile. These differences were analysed by Next-Generation Sequencing of six age groups from bone marrow mesenchymal stem cells. ... -
Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their tole in ageing
Fafián Labora, Juan Antonio; Morente-López, Miriam; Sánchez-Dopico, María José; Arntz, O.J.; Van de Loo, F.J.; De-Toro, Javier; Arufe, M.C. (Springer Nature, 2020-01-03)[Abstract] Introduction: This study assessed whether mesenchymal stem cell (MSC)-derived extracellular vesicles influenced ageing and pluripotency markers in cell cultures where they are added. Methods: MSC-derived ... -
Therapeutic Potential for Regulation of the Nuclear Factor Kappa-B Transcription Factor p65 to Prevent Cellular Senescence and Activation of Pro-Inflammatory in Mesenchymal Stem Cells
Mato-Basalo, Rocío; Morente-López, Miriam; Arntz, O.J.; Van de Loo, F.J.; Fafián Labora, Juan Antonio; Arufe, M.C. (MDPI, 2021-03-25)[Abstract] Mesenchymal stem cells have an important potential in the treatment of age-related diseases. In the last years, small extracellular vesicles derived from these stem cells have been proposed as cell-free ...