Listar por tema "Regenerative medicine"
Mostrando ítems 1-6 de 6
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Cell therapy and tissue engineering for cartilage repair
(IntechOpen, 2018-02-14)[Abstract] The integrity of the articular cartilage is necessary for the proper functioning of the diarthrodial joint. The self-repair capacity of this tissue is very limited and, currently, there is no effective treatment ... -
Human cartilage engineering in an in vitro repair model using collagen scaffolds and mesenchymal stromal cells
(Ivyspring, 2017-09-28)[Abstract] The purpose of this study was to investigate cartilage repair of in vitro lesion models using human bone marrow mesenchymal stromal cells (hBMSCs) with different collagen (Col) scaffolds. Lesions were made ... -
Induced pluripotent stem cells for cartilage repair: current status and future perspectives
(AO Research Institute Davos, 2018-09-11)[Abstract] The establishment of cartilage regenerative medicine is an important clinical issue, but the search for cell sources able to restore cartilage integrity proves to be challenging. Human mesenchymal stromal cells ... -
Non-viral Gene Delivery to Human Mesenchymal Stem Cells: A Practical Guide Towards Cell Engineering
(BioMed Central, 2023)[Abstract] In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the field of cell therapy for treating cartilage and bone injuries. Despite the tri-lineage multipotency, proliferative properties, ... -
Regulation of Angiogenesis Discriminates Tissue Resident MSCs from Effective and Defective Osteogenic Environments
(MDPI, 2020-05-28)[Abstract] Background: The biological mechanisms that contribute to atrophic long bone non-union are poorly understood. Multipotential mesenchymal stromal cells (MSCs) are key contributors to bone formation and are ... -
Versatility of induced Pluripotent Stem Cells (iPSCs) for improving the knowledge on musculoskeletal diseases
(MDPI, 2020-08-25)[Abstract] Induced pluripotent stem cells (iPSCs) represent an unlimited source of pluripotent cells capable of di erentiating into any cell type of the body. Several studies have demonstrated the valuable use of iPSCs ...