Listar por tema "GWAS"
Mostrando ítems 1-6 de 6
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Fast search of third-order epistatic interactions on CPU and GPU clusters
(Sage Publications Ltd., 2019-05-27)[Abstract] Genome-Wide Association Studies (GWASs), analyses that try to find a link between a given phenotype (such as a disease) and genetic markers, have been growing in popularity in the recent years. Relations between ... -
Fiuncho: a program for any-order epistasis detection in CPU clusters
(Springer, 2022)[Abstract]: Epistasis can be defined as the statistical interaction of genes during the expression of a phenotype. It is believed that it plays a fundamental role in gene expression, as individual genetic variants have ... -
GPU-accelerated exhaustive search for third-order epistatic interactions in case–control studies
(Elsevier Ltd, 2015)[Abstract] Interest in discovering combinations of genetic markers from case–control studies, such as Genome Wide Association Studies (GWAS), that are strongly associated to diseases has increased in recent years. Detecting ... -
High-speed exhaustive 3-locus interaction epistasis analysis on FPGAs
(Elsevier B.V., 2015-07)[Abstract]: Epistasis, the interaction between genes, has become a major topic in molecular and quantitative genetics. It is believed that these interactions play a significant role in genetic variations causing complex ... -
Hybrid CPU/GPU Acceleration of Detection of 2-SNP Epistatic Interactions in GWAS
(Springer, 2014-08)[Abstract] High-throughput genotyping technologies allow the collection of up to a few million genetic markers (such as SNPs) of an individual within a few minutes of time. Detecting epistasis, such as 2-SNP interactions, ... -
RP11-362K2.2:RP11-767I20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma: a GWAS meta-analysis
(MDPI, 2021-07-16)[Abstract] Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase ...