Listar por tema "Cell death"
Mostrando ítems 1-5 de 5
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Estudio in vitro da relación entre disfunción mitocondrial e resposta inflamatoria en células mononucleares de sangue periférica
(2022)[Resumo] A artrite reumatoide (AR) é unha doenza inflamatoria e crónica de carácter autoinmune que afecta aproximadamente ao 1% da poboación mundial e que ten como principal órgano diana as articulacións sinoviais. Entre ... -
Evaluation of the in Vitro and in Vivo Efficacy of Ruthenium Polypyridyl Compounds Against Breast Cancer
(MDPI, 2021-08-18)[Abstract] The clinical success of cisplatin, carboplatin, and oxaliplatin has sparked the interest of medicinal inorganic chemistry to synthesize and study compounds with non-platinum metal centers. Despite Ru(II)–polypyridyl ... -
Hif-1α knockdown reduces glycolytic metabolism and induces cell death of human synovial fibroblasts under normoxic conditions
(Nature, 2017-06-16)[Abstract] Increased glycolysis and HIF-1α activity are characteristics of cells under hypoxic or inflammatory conditions. Besides, in normal O2 environments, elevated rates of glycolysis support critical cellular mechanisms ... -
Markov Mean Properties for Cell Death-Related Protein Classification
(Elsevier, 2014-01-31)[Abstract] The cell death (CD) is a dynamic biological function involved in physiological and pathological processes. Due to the complexity of CD, there is a demand for fast theoretical methods that can help to find new ... -
Mitochondrial dysfunction and oxidative stress in rheumatoid arthritis
(MDPI, 2022-06-12)[Abstract] Control of excessive mitochondrial oxidative stress could provide new targets for both preventive and therapeutic interventions in the treatment of chronic inflammation or any pathology that develops under an ...