• Evaluation of the in Vitro and in Vivo Efficacy of Ruthenium Polypyridyl Compounds Against Breast Cancer 

      Lenis Rojas, Óscar; Roma-Rodrigues, Catarina; Fernandes, Alexandra R.; Carvalho, Andreia; Cordeiro, Sandra; Guerra-Varela, Jorge; Sánchez, Laura; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández, Jesús J. (MDPI, 2021-08-18)
      [Abstract] The clinical success of cisplatin, carboplatin, and oxaliplatin has sparked the interest of medicinal inorganic chemistry to synthesize and study compounds with non-platinum metal centers. Despite Ru(II)–polypyridyl ...
    • Severe Neurometabolic Phenotype in NPC1−/− Zebrafish With a C-Terminal Mutation 

      Quelle Regaldie, Ana; Gandoy-Fieiras, Nerea; Villamayor, Paula R.; Maceiras, Sandra; Losada, Ana; Folgueira, Mónica; Cabezas Sáinz, Pablo; Barreiro-Iglesias, Antón; Villar López, María; Quiroga-Berdeal, María Isabel; Sánchez, Laura; Sobrido, María Jesús (Frontiers, 2023-03-17)
      [Abstract] Niemann Pick disease type C (NPC) is an autosomal recessive neurodegenerative lysosomal disorder characterized by an accumulation of lipids in different organs. Clinical manifestations can start at any age and ...
    • Zebrafish Models for the Safety and Therapeutic Testing of Nanoparticles with a Focus on Macrophages 

      Pensado-López, Alba; Fernández-Rey, Juan; Reimunde, Pedro; Crecente-Campo, José; Sánchez, Laura; Torres Andón, Fernando (MDPI, 2021-07-09)
      [Abstract] New nanoparticles and biomaterials are increasingly being used in biomedical research for drug delivery, diagnostic applications, or vaccines, and they are also present in numerous commercial products, in the ...