Listar por autor "Roca-Lema, Daniel"
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Molecular Mechanisms Involved in Inflammatory Bowel Disease and Colorectal Cancer: Novel Therapeutic Strategies
Roca-Lema, Daniel (2021)[Abstract] Chapter One Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal tract and represents an important risk factor for the onset of colorectal cancer (CRC). Hakai is ... -
Role of the E3 Ubiquitin-Ligase Hakai in Intestinal Inflammation and Cancer Bowel Disease
Roca-Lema, Daniel; Quiroga, Macarena; Khare, Vineeta; Díaz-Díaz, Andrea; Barreiro-Alonso, Aida; Rodríguez-Alonso, Andrea; Concha, Ángel; Romay, Gabriela; Cerdán, María Esperanza; Gasche, Christoph; Figueroa, Angélica (Springer Nature, 2022-10-20)[Abstract] The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the ...