Listar por autor "Lorenzo Gómez, Irene"
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Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
Nogueira Recalde, Uxía; Lorenzo Gómez, Irene; Blanco García, Francisco J; Loza, María Isabel; Grassi, Diego; Shirinsky, Valery; Shirinsky, Ivan; Lotz, Martin; Robbins, Paul D.; Domínguez, Eduardo; Caramés, Beatriz (Elsevier, 2019-07-05)[Abstract] Background. Ageing-related failure of homeostasis mechanisms contributes to articular cartilage degeneration and osteoarthritis (OA), for which disease-modifying treatments are not available. Our objective was ... -
Identification and validation of therapeutic targets in osteoarthritis and diabetes-associated osteoarthritis: Role of autophagy
Lorenzo Gómez, Irene (2022)[Resumo] O defecto nos mecanismos de homeostase, como a macroautofaxia, contribúe ao envellecemento articular e precede ao dano articular na artrose. Ademais, istos defectos poderían ser mecanismos patolóxicos nas ...