Listar por autor "Lasarte-Monterrubio, Cristina"
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Antimicrobial Diterpene Alkaloids from an Agelas citrina Sponge Collected in the Yucatán Peninsula
Pech-Puch, Dawrin; Forero, Abel M.; Fuentes-Monteverde, Juan Carlos; Lasarte-Monterrubio, Cristina; Martínez Guitián, Marta; González-Salas, Carlos; Guillén-Hernández, Sergio; Villegas-Hernández, Harold; Beceiro, Alejandro; Griesinger, Christian; Rodríguez, Jaime; Jiménez, Carlos (MDPI, 2022-04-28)[Abstract] Three new diterpene alkaloids, (+)-8-epiagelasine T (1), (+)-10-epiagelasine B (2), and (+)-12-hydroxyagelasidine C (3), along with three known compounds, (+)-ent-agelasine F (4), (+)-agelasine B (5), and ... -
Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter junii Conferred by Acquisition of blaOXA-24/40 and Genetic Characterization of the Transmission Mechanism between Acinetobacter Genomic Species
Lasarte-Monterrubio, Cristina; Guijarro, Paula; Bellés, Alba; Vázquez-Ucha, Juan Carlos; Arca-Suárez, Jorge; Fernández-Lozano, Carlos; Bou, Germán; Beceiro, Alejandro (American Society for Microbiology, 2022)[Abstract] Carbapenem resistance is increasing among Gram-negative bacteria, including the genus Acinetobacter. This study aimed to characterize, for the first time, the development of carbapenem resistance in clinical ... -
Epidemiology, resistance genomics and susceptibility of Acinetobacter species: results from the 2020 Spanish nationwide surveillance study
Lasarte-Monterrubio, Cristina; Guijarro, Paula; Alonso-Garcia, Isaac; Outeda, Michelle; Maceiras, Romina; González-Pinto, Lucía; Martínez-Guitián, Marta; Fernández-Lozano, Carlos; Vázquez-Ucha, Juan Carlos; Bou, Germán; Arca-Suárez, Jorge; Beceiro, Alejandro (European Centre for Disease Prevention and Control (ECDC), 2024-04-11)[Abstract]: Background: As increasing antibiotic resistance in Acinetobacter baumannii poses a global healthcare challenge, understanding its evolution is crucial for effective control strategies. Aim: We aimed ... -
In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa
Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-06-23)[Abstract] The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the ... -
Involvement of HisF in the persistence of Acinetobacter baumannii during a pneumonia infection
Martínez-Guitián, Marta; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Conde-Pérez, Kelly; Lasarte-Monterrubio, Cristina; Vallejo, J. A.; Bou, Germán; Poza, Margarita; Beceiro, Alejandro (Frontiers, 2019)[Abstract] Acinetobacter baumannii is currently considered one of themost problematic nosocomial microorganisms. In the present work the hisF gene from the ATCC 17978 strain and the AbH12O-A2 clinical isolate of A. baumannii ... -
Marine Organisms from the Yucatan Peninsula (Mexico) as a Potential Natural Source of Antibacterial Compounds
Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Gómez, Patricia; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez-Ucha, Juan Carlos; Novoa Olmedo, María Lourdes; Guillén-Hernández, Sergio; Villegas-Hernández, Harold; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-07-18)[Abstract] A total of 51 sponges (Porifera) and 13 ascidians (Chordata) were collected on the coast of the Yucatan Peninsula (Mexico) and extracted with organic solvents. The resulting extracts were screened for antibacterial ... -
Resistencia antibiótica en Acinetobacter spp. y Enterobacter cloacae complex: epidemiología, mecanismos y tratamiento
Lasarte-Monterrubio, Cristina (2024)[Resumo] A resistencia antibiótica, con Acinetobacter baumannii e Enterobacter cloacae complex (ECC) como microorganismos clave, constitúe unha das principais causas de morbimortalidade a nivel mundial. O estudo destas ...