Listar por autor "Lages, Marta Afonso"
Mostrando ítems 1-5 de 5
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FrpA Is the Outer Membrane Piscibactin Transporter in Vibrio Anguillarum: Structural Elements in Synthetic Piscibactin Analogues Required for Transport
Lages, Marta Afonso; De la Fuente, Carmen; Ageitos, Lucía; Martínez Matamoros, Diana; Rodríguez, Jaime; Balado, Miguel; Jiménez, Carlos; Lemos, Manuel L. (Springer Nature, 2021-11-18)[Abstract] Piscibactin (Pcb) is a labile siderophore widespread among Vibrionaceae. Its production is a major virulence factor of some fish pathogens such as Photobacterium damselae subsp. piscicida and Vibrio anguillarum. ... -
Identification of Key Functions Required for Production and Utilization of the Siderophore Piscibactin Encoded by the High-Pathogenicity Island irp-HPI in Vibrionaceae
Lages, Marta Afonso; Ageitos, Lucía; Rodríguez, Jaime; Jiménez, Carlos; Lemos, Manuel L.; Balado, Miguel (MDPI, 2022)[Abstract] Piscibactin is a widespread siderophore system present in many different bacteria, especially within the Vibrionaceae family. Previous works showed that most functions required for biosynthesis and transport of ... -
O-versus S-Metal Coordination of the Thiocarboxylate Group: An NMR Study of the Two Tautomeric Forms of the Ga(III)-Photoxenobactin E Complex
Buedenbender, Larissa; Ageitos, Lucía; Lages, Marta Afonso; Platas-Iglesias, Carlos; Balado, Miguel; Lemos, Manuel L.; Rodríguez, Jaime; Jiménez, Carlos (American Chemical Society, 2024-02-22)[Abstract] Photoxenobactin E (1) is a natural product with an unusual thiocarboxylic acid terminus recently isolated from an entomopathogenic bacterium. The biosynthetic gene cluster associated with photoxenobactin E, and ... -
Structural Requirements for Ga3+ Coordination in Synthetic Analogues of the Siderophore Piscibactin Deduced by Chemical Synthesis and Density Functional Theory Calculations
De la Fuente, Carmen; Ageitos, Lucía; Lages, Marta Afonso; Martínez Matamoros, Diana; Forero, Abel M.; Balado, Miguel; Lemos, Manuel L.; Rodríguez, Jaime; Jiménez, Carlos (American Chemical Society, 2023-05-04)[Abstract] Stereoselective total synthesis of several analogues of piscibactin (Pcb), the siderophore produced by different pathogenic Gram-negative bacteria, was performed. The acid-sensitive α-methylthiazoline moiety was ... -
The Siderophore Piscibactin Is a Relevant Virulence Factor for Vibrio anguillarum Favored at Low Temperatures
Balado, Miguel; Lages, Marta Afonso; Fuentes-Monteverde, Juan Carlos; Martínez Matamoros, Diana; Rodríguez, Jaime; Jiménez, Carlos; Lemos, Manuel L. (Frontiers, 2018-08-02)[Abstract] Vibrio anguillarum causes vibriosis, a hemorrhagic septicaemia that affects many cultured marine fish species worldwide. Two catechol siderophores, vanchrobactin and anguibactin, were previously identified in ...