• Central ghrelin regulates peripheral lipid metabolism in a growth hormone-independent fashion 

      Sangiao-Alvarellos, Susana; Vázquez, María J.; Varela, Luis; Nogueiras, Rubén; Saha, Asish K.; Cordido, Fernando; López, Miguel; Diéguez, Carlos (Oxford para Endocrine Society, 2009-10-01)
      [Abstract] GH plays a major role in the regulation of lipid metabolism and alterations in GH axis elicit major changes in fat distribution and mobilization. For example, in patients with GH deficiency (GHD) or in mice ...
    • Ghrelin and lipid metabolism: key partners in energy balance 

      Varela, Luis; Vázquez, María J.; Cordido, Fernando; Nogueiras, Rubén; Vidal-Puig, Antonio; Diéguez, Carlos; López, Miguel (Bioscientifica para Society for Endocrinoloogy, 2011-04-01)
      [Abstract] Ghrelin, the endogenous ligand of the GH secretagogue receptor, has a pleiotropic role in the modulation of energy balance. Recent evidence has demonstrated that besides its orexigenic role, ghrelin regulates ...
    • Influence of ghrelin and growth hormone deficiency on AMP-activated protein kinase and hypothalamic lipid metabolism 

      Sangiao-Alvarellos, Susana; Varela, Luis; Vázquez, María J.; Boit, K. Da; Saha, A.K.; Cordido, Fernando; Diéguez, Carlos; López, Miguel (Wiley, 2010-03-08)
      [Abstract] Current evidence demonstrates that the stomach-derived hormone ghrelin, a potent growth hormone (GH) secretagogue, promotes feeding through a mechanism involving the short-term activation of hypothalamic ...