Listar por autor "Forero, Abel M."
Mostrando ítems 1-5 de 5
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Antifungal Potential of Marine Organisms of the Yucatan Peninsula (Mexico) against Medically Important Candida spp.
Pech-Puch, Dawrin; Grilo, Diana; Calva Pérez, Susana Eunice; Pedras, Andreia; Villegas-Hernández, Harold; Guillén-Hernández, Sergio; Díaz-Gamboa, Raúl E.; Forero, Abel M.; Rodríguez, Jaime; Lenis Rojas, Óscar; Jiménez, Carlos; Pimentel, Catarina (MDPI, 2023-01-06)[Abstract] Invasive fungal infections represent a global health threat. They are associated with high mortality and morbidity rates, partly due to the ineffectiveness of the available antifungal agents. The rampant increase ... -
Antimicrobial Diterpene Alkaloids from an Agelas citrina Sponge Collected in the Yucatán Peninsula
Pech-Puch, Dawrin; Forero, Abel M.; Fuentes-Monteverde, Juan Carlos; Lasarte-Monterrubio, Cristina; Martínez Guitián, Marta; González-Salas, Carlos; Guillén-Hernández, Sergio; Villegas-Hernández, Harold; Beceiro, Alejandro; Griesinger, Christian; Rodríguez, Jaime; Jiménez, Carlos (MDPI, 2022-04-28)[Abstract] Three new diterpene alkaloids, (+)-8-epiagelasine T (1), (+)-10-epiagelasine B (2), and (+)-12-hydroxyagelasidine C (3), along with three known compounds, (+)-ent-agelasine F (4), (+)-agelasine B (5), and ... -
Connection of Isolated Stereoclusters by Combining 13C-RCSA, RDC, and J-Based Configurational Analyses and Structural Revision of a Tetraprenyltoluquinol Chromane Meroterpenoid from Sargassum muticum
Fuentes-Monteverde, Juan Carlos; Nath, Nilamoni; Forero, Abel M.; Balboa, Elena M.; Navarro-Vázquez, Armando; Griesinger, Christian; Jiménez, Carlos; Rodríguez, Jaime (MDPI, 2022)[Abstract] The seaweed Sargassum muticum, collected on the southern coast of Galicia, yielded a tetraprenyltoluquinol chromane meroditerpene compound known as 1b, whose structure is revised. The relative configuration of ... -
Structural Requirements for Ga3+ Coordination in Synthetic Analogues of the Siderophore Piscibactin Deduced by Chemical Synthesis and Density Functional Theory Calculations
De la Fuente, Carmen; Ageitos, Lucía; Lages, Marta Afonso; Martínez Matamoros, Diana; Forero, Abel M.; Balado, Miguel; Lemos, Manuel L.; Rodríguez, Jaime; Jiménez, Carlos (American Chemical Society, 2023-05-04)[Abstract] Stereoselective total synthesis of several analogues of piscibactin (Pcb), the siderophore produced by different pathogenic Gram-negative bacteria, was performed. The acid-sensitive α-methylthiazoline moiety was ... -
Uncovering the Cyanobacterial Chemical Diversity: The Search for Novel Anticancer Compounds
Ferreira, Leonor; Sousa, Maria Lígia; Ribeiro, Tiago; Morais, João; Forero, Abel M.; Branco, Raquel Castelo; Leão, Pedro N.; Preto, Marco Aurélio Correia; Urbatzka, Ralph; Szemerédi, Nikoletta; Spengler, Gabriella; Jiménez, Carlos; Rodríguez, Jaime; Vasconcelos, Vitor; Reis, Mariana (MDPI, 2022-09-15)[Abstract] Cancer has a tremendous negative socio-economic impact on our society. Thus, the discovery of new and more effective anticancer drugs is of utmost importance. To address this societal challenge, the main goal ...