Browsing by Author "Eaton, Philip"

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Analysis of mitochondrial proteins in the surviving myocardium after ischemia identifies mitochondrial pyruvate carrier expression as possible mediator of tissue

Fernández Caggiano, Mariana; Prysyazhna, Oleksandra; Barallobre-Barreiro, Javier; Calviño Santos, Ramón; Aldama López, Guillermo; Crespo-Leiro, María Generosa; Eaton, Philip; Doménech, Nieves (American Society for Biochemistry and Molecular Biology, 2016-01-01)
Mitochondrial Pyruvate Carrier Abundance Mediates Pathological Cardiac Hypertrophy

Fernández-Caggiano, Mariana; Kamynina, Alisa; Francois, Asvi A.; Prysyazhna, Oleksandra; Eykyn, Thomas R.; Krasemann, Susanne; Crespo-Leiro, María Generosa; García-Vieites, M.; Bianchi, Katiuscia; Morales, Valle; Doménech, Nieves; Eaton, Philip (Springer Nature, 2020-10-26)

[Abstract] Cardiomyocytes rely on metabolic substrates, not only to fuel cardiac output, but also for growth and remodelling during stress. Here we show that mitochondrial pyruvate carrier (MPC) abundance mediates ...