Listar por autor "De la Fuente, Carmen"
Mostrando ítems 1-3 de 3
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Convergent Total Synthesis of the Siderophore Piscibactin as Its Ga3+ Complex
De la Fuente, Carmen; Segade, Yuri; Valderrama Pereira, Andrea Katherine; Rodríguez, Jaime; Jiménez, Carlos (American Chemical Society, 2021-01-15)[Abstract] The siderophore piscibactin is a key virulence factor involved in the iron uptake of pathogenic bacteria Photobacterium damselae subsp. piscicida and Vibrio anguillarum, responsible for the fish diseases ... -
FrpA Is the Outer Membrane Piscibactin Transporter in Vibrio Anguillarum: Structural Elements in Synthetic Piscibactin Analogues Required for Transport
Lages, Marta Afonso; De la Fuente, Carmen; Ageitos, Lucía; Martínez Matamoros, Diana; Rodríguez, Jaime; Balado, Miguel; Jiménez, Carlos; Lemos, Manuel L. (Springer Nature, 2021-11-18)[Abstract] Piscibactin (Pcb) is a labile siderophore widespread among Vibrionaceae. Its production is a major virulence factor of some fish pathogens such as Photobacterium damselae subsp. piscicida and Vibrio anguillarum. ... -
Structural Requirements for Ga3+ Coordination in Synthetic Analogues of the Siderophore Piscibactin Deduced by Chemical Synthesis and Density Functional Theory Calculations
De la Fuente, Carmen; Ageitos, Lucía; Lages, Marta Afonso; Martínez Matamoros, Diana; Forero, Abel M.; Balado, Miguel; Lemos, Manuel L.; Rodríguez, Jaime; Jiménez, Carlos (American Chemical Society, 2023-05-04)[Abstract] Stereoselective total synthesis of several analogues of piscibactin (Pcb), the siderophore produced by different pathogenic Gram-negative bacteria, was performed. The acid-sensitive α-methylthiazoline moiety was ...