• Altered pathways in methylome and transcriptome longitudinal analysis of normal weight and bariatric surgery women 

      Nicoletti, C. F.; Pinhel, M.A.S.; Noronha, N.Y.; De Oliveira, B.A.; Salgado Junior, W.; Jácome, M. A.; Díaz-Lagares, Angel; Casanueva, F.; Crujeiras, A. B.; Nonino, C. B. (NLM (Medline), 2020-04-15)
      [Abstract] DNA methylation could provide a link between environmental, genetic factors and weight control and can modify gene expression pattern. This study aimed to identify genes, which are differentially expressed and ...
    • Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma 

      Sanegre, Sabina; Eritja, Núria; Andrea, Carlos de; Díaz-Martín, Juan; Díaz-Lagares, Angel; Jácome, M. A.; Salguero Aranda, Carmen; García-Ros, David; Davidson, Ben; López-López, Rafael; Melero, Ignacio; Navarro, Samuel; Ramón y Cajal, Santiago; Alava, Enrique de; Matias-Guiu, Xavier; Noguera, Rosa (Frontiers, 2021)
      [Abstract] The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding ...
    • DNA methylation screening after roux-en Y gastric bypass reveals the epigenetic signature stems from genes related to the surgery per se 

      Nicoletti, C. F.; Pinhel, M.A.S.; Díaz-Lagares, Angel; Casanueva, F.; Jácome, M. A.; Pinhanelli, Vitor Caressato; De Oliveira, B.A.; Crujeiras, A. B.; Nonino, C. B. (Springer Nature, 2019-05-27)
      [Abstract] Background/objectives: Obesity has been associated with gene methylation regulation. Recent studies have shown that epigenetic signature plays a role in metabolic homeostasis after Roux-en Y gastric bypass ...