Listar por autor "Cerdán, María Esperanza"
Mostrando ítems 1-19 de 19
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Cellulases from thermophiles found by metagenomics
Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Cerdán, María Esperanza; Rodríguez-Belmonte, Esther; Becerra, Manuel; González-Siso, María-Isabel (MDPI, 2018-07-10)[Abstract] Cellulases are a heterogeneous group of enzymes that synergistically catalyze the hydrolysis of cellulose, the major component of plant biomass. Such reaction has biotechnological applications in a broad spectrum ... -
Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications
Barreiro-Alonso, Aida; Cámara-Quílez, María; Salamini-Montemurri, Martín; Lamas, Mónica; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Martínez-Iglesias, Olaia; Figueroa, Angélica; Cerdán, María Esperanza (MDPI, 2019-11-05)[Abstract] High mobility group box B (HMGB) proteins are pivotal in the development of cancer. Although the proteomics of prostate cancer (PCa) cells has been reported, the involvement of HMGB proteins and their interactome ... -
Delineating the HMGB1 and HMGB2 Interactome in Prostate and Ovary Epithelial Cells and Its Relationship With Cancer
Barreiro-Alonso, Aida; Lamas, Mónica; García-Díaz, Rosa; Rodríguez-Belmonte, Esther; Yu, Lu; Pardo, Mercedes; Choudhary, Jyoti; Cerdán, María Esperanza (Impact Journals, 2018-04-10)[Abstract] High Mobility Group B (HMGB) proteins are involved in cancer progression and in cellular responses to platinum compounds used in the chemotherapy of prostate and ovary cancer. Here we use affinity purification ... -
HMG Proteins from Molecules to Disease [Editorial]
Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2022-02-17) -
HMGB1 Protein Interactions in Prostate and Ovary Cancer Models Reveal Links to RNA Processing and Ribosome Biogenesis through NuRD, THOC and Septin Complexes
Barreiro-Alonso, Aida; Lamas, Mónica; Lorenzo Catoira, Lidia; Pardo, Mercedes; Yu, Lu; Choudhary, Jyoti S.; Cerdán, María Esperanza (MDPI, 2021-09-18)[Abstract] This study reports the HMGB1 interactomes in prostate and ovary cancer cells lines. Affinity purification coupled to mass spectrometry confirmed that the HMGB1 nuclear interactome is involved in HMGB1 known ... -
Hot Spring Metagenomics
López-López, Olalla; Cerdán, María Esperanza; González-Siso, María-Isabel (Multidisciplinary Digital Publishing Institute, 2013)Hot springs have been investigated since the XIX century, but isolation and examination of their thermophilic microbial inhabitants did not start until the 1950s. Many thermophilic microorganisms and their viruses have ... -
Introducción
Méndez, Josefina; Cerdán, María Esperanza; Rodríguez, Ana (Universidade da Coruña, 1994) -
Ixr1 Regulates Ribosomal Gene Transcription and Yeast Response to Cisplatin
Vizoso-Vázquez, Ángel; Lamas, Mónica; González-Siso, María-Isabel; Cerdán, María Esperanza (Springer Nature, 2018-02-15)[Abstract] Ixr1 is a Saccharomyces cerevisiae HMGB protein that regulates the hypoxic regulon and also controls the expression of other genes involved in the oxidative stress response or re-adaptation of catabolic and ... -
Optimization of Saccharomyces cerevisiae α-galactosidase production and application in the degradation of raffinose family oligosaccharides
Álvarez Cao, María E.; Cerdán, María Esperanza; González-Siso, María-Isabel; Becerra, Manuel (BMC, 2019-10-10)[Abstract] Background: α-Galactosidases are enzymes that act on galactosides present in many vegetables, mainly legumes and cereals, have growing importance with respect to our diet. For this reason, the use of their ... -
Predicciones de función basadas en la estructura del gen. Análisis de orfs de función desconocida
Cerdán, María Esperanza; Freire-Picos, María Ángeles (Universidade da Coruña, 1997) -
Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin
Rodríguez Lombardero, Silvia; Rodríguez-Belmonte, Esther; González-Siso, María-Isabel; Vizoso-Vázquez, Ángel; Valdiglesias, Vanessa; Laffon, Blanca; Cerdán, María Esperanza (Multidisciplinary Digital Publishing Institute, 2014)[Abstract] Sky1 is the only member of the SR (Serine–Arginine) protein kinase family in Saccharomyces cerevisiae. When yeast cells are treated with the anti-cancer drug cisplatin, Sky1 kinase activity is necessary to produce ... -
Role of the E3 Ubiquitin-Ligase Hakai in Intestinal Inflammation and Cancer Bowel Disease
Roca-Lema, Daniel; Quiroga, Macarena; Khare, Vineeta; Díaz-Díaz, Andrea; Barreiro-Alonso, Aida; Rodríguez-Alonso, Andrea; Concha, Ángel; Romay, Gabriela; Cerdán, María Esperanza; Gasche, Christoph; Figueroa, Angélica (Springer Nature, 2022-10-20)[Abstract] The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the ... -
Terapia génica y regulación tejido-específica
Cerdán, María Esperanza (Universidade da Coruña, 1993) -
Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer [Review]
Lamas, Mónica; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Cámara-Quílez, M.; Cerdán, María Esperanza (MDPI, 2023-04-11)[Abstract] Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of ... -
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use
Salamini-Montemurri, Martín; Lamas, Mónica; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Cerdán, María Esperanza (MDPI, 2020-04-21)[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor. In this review we aim to highlight ... -
The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer
Salamini-Montemurri, Martín; Vizoso-Vázquez, Ángel; Barreiro-Alonso, Aida; Lorenzo-Catoira, Lidia; Rodríguez-Belmonte, Esther; Cerdán, María Esperanza; Lamas, Mónica (MDPI, 2024-03-07)[Abstract] Human high-mobility group-B (HMGB) proteins regulate gene expression in prostate cancer (PCa), a leading cause of oncological death in men. Their role in aggressive PCa cancers, which do not respond to hormonal ... -
The HMGB Protein KlIxr1, a DNA Binding Regulator of Kluyveromyces lactis Gene Expression Involved in Oxidative Metabolism, Growth, and dNTP Synthesis
Rico Díaz, Agustín; Barreiro-Alonso, Aida; Rey-Souto, Cora; Becerra, Manuel; Lamas, Mónica; Cerdán, María Esperanza; Vizoso-Vázquez, Ángel (MDPI, 2021-08-21)[Abstract] In the traditional fermentative model yeast Saccharomyces cerevisiae, ScIxr1 is an HMGB (High Mobility Group box B) protein that has been considered as an important regulator of gene transcription in response ... -
The HMGB1-2 Ovarian Cancer Interactome: the Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response
Cámara-Quílez, María; Barreiro-Alonso, Aida; Vizoso-Vázquez, Ángel; Rodríguez-Belmonte, Esther; Quindós-Varela, María; Lamas, Mónica; Cerdán, María Esperanza (MDPI, 2020-08-27)[Abstract] High mobility group box B (HMGB) proteins are overexpressed in different types of cancers such as epithelial ovarian cancers (EOC). We have determined the first interactome of HMGB1 and HMGB2 in epithelial ovarian ... -
Thermus thermophilus as a Source of Thermostable Lipolytic Enzymes
López-López, Olalla; Cerdán, María Esperanza; González-Siso, María-Isabel (Multidisciplinary Digital Publishing Institute, 2015)Lipolytic enzymes, esterases (EC 3.1.1.1) and lipases (EC 3.1.1.3), catalyze the hydrolysis of ester bonds between alcohols and carboxylic acids, and its formation in organic media. At present, they represent about 20% of ...