• Deep-Sequencing Reveals Broad Subtype-Specific HCV Resistance Mutations Associated with Treatment Failure 

      Chen, Qian; Perales, Celia; Soria, María Eugenia; García-Cehic, Damir; Gregori, Josep; Rodríguez-Frías, Francisco; Buti, M.; Crespo, Javier; Calleja, J.L.; Tabernero, David; Vila Salvador, Marta; Lázaro, Fernando; Rando-Segura, Ariadna; Nieto-Aponte, Leonardo; Llorens-Revull, Meritxell; Cortese, Maria Francesca; Fernández, Irati; Castellote, José; Niubó, Jordi; Imaz, Arkaitz; Delgado, Manuel; Cañizares, Angelina; Castro-Iglesias, Ángeles (Elsevier, 2019-12-16)
      [Abstract] A percentage of hepatitis C virus (HCV)-infected patients fail direct acting antiviral (DAA)-based treatment regimens, often because of drug resistance-associated substitutions (RAS). The aim of this study was ...
    • Effectiveness and safety of sofosbuvir‐based regimens plus an NS5A inhibitor for patients with HCV genotype 3 infection and cirrhosis: results of a multicenter real‐life cohort 

      Alonso, S.; Riveiro-Barciela, M.; Fernández, I.; Rincón, D.; Real, Y.; Llerena, S.; Gea, F.; Olveira, A.; Fernández-Carrillo, C.; Polo, B.; Carrión, J.A.; Gómez, A.; Devesa, M.J.; Baliellas, C.; Castro-Iglesias, Ángeles; Ampuero, J.; Granados, R.; Pascasio, J.M.; Rubín, A.; Salmerón, J.; Badia, E.; Planas, J.M.M.; Lens, S.; Turnes, J.; Montero, J.L.; Buti, M.; Esteban, R.; Fernández-Rodríguez, C.M. (Wiley, 2016-11-09)
      [Abstract] Patients with HCV genotype 3 (GT3) infection and cirrhosis are currently the most difficult to cure. We report our experience with sofosbuvir+daclatasvir (SOF+DCV) or sofosbuvir/ledipasvir (SOF/LDV), with or ...
    • Efficacy and safety of HCV-treatment with direct-acting antiviral agents interferon-free, in patients with severe renal impairment in clinical practice 

      Cabezas, Joaquín; Londoño, M.C.; Llerena, S.; Muñoz, R.; Baliellas, C.; Buti, M.; Pascasio, J.M.; Sáez-Royuela, F.; García-Samaniego, J.; Vega, J. de la; Sánchez-Pobre, P.; Álvarez-Navascues, C.; Carrión, J.A.; Gea, F.; Morillas, R.M.; Fernández-Bermejo, M.; Castro-Iglesias, Ángeles; Rivero, M.; Fernández, J.R.; Berenguer, M.; Moreno, J.J.; Rincón, D.; Calleja, J.L.; Crespo, J. (Elsevier, 2016)