• Epigenetics as a therapeutic target in osteoarthritis 

      Núñez-Carro, Carmen; Blanco-Blanco, Margarita; Villagrán-Andrade, Karla Mariuxi; Blanco García, Francisco J; Andrés, María C. de (MDPI, 2023-01-21)
      [Abstract] Osteoarthritis (OA) is a heterogenous, complex disease affecting the integrity of diarthrodial joints that, despite its high prevalence worldwide, lacks effective treatment. In recent years it has been discovered ...
    • Nitric Oxide Compounds Have Different Effects Profiles on Human Articular Chondrocyte Metabolism 

      Andrés, María C. de; Maneiro, Emilia; Martín, Miguel A.; Arenas, Joaquín; Blanco García, Francisco J (BioMed Central, 2013-09-11)
      [Abstract] Introduction. The pathogenesis of osteoarthritis (OA) is characterized by the production of high amounts of nitric oxide (NO), as a consequence of up-regulation of chondrocyte-inducible nitric oxide synthase ...