Listar por autor "Cordido, Fernando"
Mostrando ítems 41-60 de 83
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Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect
Cordido, Fernando; Isidro, María Luisa; Nemina, Rosa; Sangiao-Alvarellos, Susana (Bentham Science, 2009)[Abstract] The first “growth hormone secretagogues” (GHSs) were discovered by Bowers et al. in 1977. In 1996 the GHSs receptor (GHS-R 1a) was cloned. The endogenous ligand for this receptor, ghrelin, was not identified ... -
Ghrelin and lipid metabolism: key partners in energy balance
Varela, Luis; Vázquez, María J.; Cordido, Fernando; Nogueiras, Rubén; Vidal-Puig, Antonio; Diéguez, Carlos; López, Miguel (Bioscientifica para Society for Endocrinoloogy, 2011-04-01)[Abstract] Ghrelin, the endogenous ligand of the GH secretagogue receptor, has a pleiotropic role in the modulation of energy balance. Recent evidence has demonstrated that besides its orexigenic role, ghrelin regulates ... -
Ghrelin in obesity, physiological and pharmacological considerations
Álvarez-Castro, Paula; Pena, Lara; Cordido, Fernando (Bentham, 2013-04)[Abstract] The aim of this review is to summarize the physiological and pharmacological aspects of ghrelin. Obesity can be defined as an excess of body fat and is associated with significant disturbances in metabolic and ... -
Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism
Sangiao-Alvarellos, Susana; Helming, Steffen; Vázquez, María J.; Klussmann, Sven; Cordido, Fernando (Elsevier, 2011)[Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ... -
Giant non-functioning pituitary adenoma: clinical characteristics and therapeutic outcomes
Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; Guerrero-Pérez, Fernando; Rodríguez Berrocal, Víctor; Vior, Carlos; Cordido, Fernando; Villabona, Carles; Díez, Juan J. (Thieme, 2020-01-02)[Abstract] Background: Giant pituitary adenoma (≥4 cm) is a rare tumor whose clinical features and prognosis are not well known. Aim: To evaluate the clinical characteristics and therapeutic outcomes of giant non-functioning ... -
Gonadotrophin-releasing hormone agonist-induced pituitary adenoma apoplexy and casual finding of a parathyroid carcinoma: a case report and review of literature
Triviño, Vanessa; Fidalgo, Olga; Juane, Antía; Pombo-Otero, Jorge; Cordido, Fernando (Baishideng Publishing Group, 2019-10-26)[Absatract] BACKGROUND Pituitary apoplexy represents one of the most serious, life threatening endocrine emergencies that requires immediate management. Gonadotropin-releasing hormone agonist (GnRHa) can induce pituitary ... -
Growth hormone, ghrelin and peptide YY secretion after oral glucose administration in healthy and obese women
Outeiriño-Blanco, Elena; García-Buela, Jesús; Sangiao-Alvarellos, Susana; Pértega-Díaz, Sonia; Martínez-Ramonde, T.; Cordido, Fernando (Thieme, 2011-06-10)[Abstract] The mechanism of the altered GH secretion in obesity is unclear. There is evidence that oral glucose (OG) administration initially decreases and subsequently stimulates GH secretion. Ghrelin is a peptide that ... -
Hambre y saciedad
Cordido, Fernando (Universidade da Coruña, 2005) -
Importance of exercise in the control of metabolic and inflammatory parameters at the moment of onset in type 1 diabetic subjects
Martínez-Ramonde, T.; Alonso, N.; Cordido, Fernando; Cervelló, E.; Cañizares, Angelina; Martínez-Peinado, P.; Sempere, J.M.; Roche, E. (Thieme, 2014-05-05)[Abstract] The onset of type 1 diabetes coincides with the final phase of β-cell destruction. In some cases, this period is characterized by the presence of a functional reserve of β-cells, favouring an adequate metabolic ... -
Influence of ghrelin and growth hormone deficiency on AMP-activated protein kinase and hypothalamic lipid metabolism
Sangiao-Alvarellos, Susana; Varela, Luis; Vázquez, María J.; Boit, K. Da; Saha, A.K.; Cordido, Fernando; Diéguez, Carlos; López, Miguel (Wiley, 2010-03-08)[Abstract] Current evidence demonstrates that the stomach-derived hormone ghrelin, a potent growth hormone (GH) secretagogue, promotes feeding through a mechanism involving the short-term activation of hypothalamic ... -
Maternal and perinatal outcomes after bariatric surgery: a spanish multicenter study
González, Irene; Rubio, Miguel A.; Cordido, Fernando; Bretón, Irene; Morales, María J.; Vilarrasa, Nuria; Monereo, Susana; Lecube, Albert; Caixás, Assumpta; Vinagre, Irene; Goday, Albert; García Luna, Pedro Pablo (Springer, 2014-08-15)[Abstract] Background. Bariatric surgery (BS) has become more frequent among women of child-bearing age. Data regarding the underlying maternal and perinatal risks are scarce. The objective of this nationwide study is to ... -
Metabolic recovery after weight loss surgery is reflected in serum microRNAs
Sangiao-Alvarellos, Susana; Theofilatos, Konstantinos; Barwari, Temo; Gutmann, Clemens; Takov, Kaloyan; Singh, Bhawana; Juiz-Valiña, Paula; Varela-Rodríguez, Bárbara María; Outeiriño-Blanco, Elena; Duregotti, Elisa; Zampetaki, Anna; Lunger, Lukas; Ebenbichler, Christoph; Tilg, Herbert; García-Brao, María Jesús; Willeit, Peter; Mena, Enrique; Kiechl, Stefan; Cordido, Fernando; Mayr, Manuel (BMJ Publishing Group, 2020-10-01)[Abstract] INTRODUCTION: Bariatric surgery offers the most effective treatment for obesity, ameliorating or even reverting associated metabolic disorders, such as type 2 diabetes. We sought to determine the effects of ... -
MiR-19 family impairs adipogenesis by the downregulation of the PPARγ transcriptional network
Juiz-Valiña, Paula; Varela-Rodríguez, Bárbara María; Outeiriño-Blanco, Elena; García-Brao, María Jesús; Mena, Enrique; Cordido, Fernando; Sangiao-Alvarellos, Susana (MDPI, 2022-12-13)[Abstract] microRNAs (miRNAs) are a class of small endogenous RNA that play pivotal roles in both the differentiation and function of adipocytes during the development of obesity. Despite this, only a few miRNA families ... -
Mortality in acromegaly diagnosed in older individuals in Spain is higher in women compared to the general spanish population
Biagetti, Betina; Iglesias, Pedro; Villar-Taibo, Rocío; Moure, María-Dolores; Paja, Miguel; Araújo-Castro, Marta; Ares, Jessica; Álvarez-Escola, Cristina; Vicente, Almudena; Álvarez Guivernau, Èlia; Novoa-Testa, Iria; Guerrero Pérez, Fernando; Cámara, Rosa; Lecumberri, Beatriz; García Gómez, Carlos; Bernebéu, Ignacio; Manjón, Laura; Gaztambide, Sonia; Cordido, Fernando; Webb, Susan M.; Menéndez-Torre, Edelmiro Luis; Díez, Juan J.; Simó, Rafael; Puig-Domingo, Manel (Oxford Academic, 2023-03-14)[Abstract] Context: There are no data on mortality of acromegaly diagnosed in older individuals. Objective: This work aimed to compare clinical characteristics, growth hormone-related comorbidities, therapeutic approaches, ... -
Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015)
Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; García-Sancho, Paula; Díez, Juan José; Cordido, Fernando; Villabona, Carles (Elsevier, 2017-04-04)[Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. Design ... -
Nutrición y ejercicio
Cordido, Fernando (Universidade da Coruña, 2005) -
Obesity, adipose tissue, inflammation and update on obesity management
Cordido, Fernando; García-Mayor, Ricardo V.; Larranaga, Alejandra (Symbiosis, 2014-11-12)[Abstract] Obesity is a serious, common and growing problem. Obesity can be defined as an excess of body fat. Its clinical management is complex and frequently unsuccessful. It has only recently been regarded as a chronic ... -
Observational, multicentre study to evaluate the effectiveness in routine clinical practice of Lanreotide Autogel 120 mg at extended dosing intervals (>4 weeks) for the treatment of acromegaly: SOMACROL study
Álvarez Escolá, Cristina; Fajardo, Carmen; Marazuela, Mónica; Cordido, Fernando; Venegas, Eva; Pablos Velasco, Pedro de; Piedrola Maroto, Gonzalo; Olvera Márquez, María del Pilar; Pavón de Paz, Isabel; Carvalho, Davide; Romero, Carmen; De la Cruz, Guillermo; Bernabéu, Ignacio (Bioscientifica, 2018-05) -
Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test
Pena-Bello, Lara; Seoane-Pillado, Teresa; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Cordido, María; Cordido, Fernando (Elsevier para European Federation of Internal Medicine, 2017-06-09)[Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ... -
Patología tiroidea en atención primaria
Núñez Vázquez, Ángel; Cordido, Fernando; Gómez Gómez, Natalia; Lois Rodríguez, Marta; Cordido, María; Louro González, Arturo (Elsevier, 2016-12)