Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethers
Use este enlace para citar
http://hdl.handle.net/2183/442Coleccións
- GI-SA - Artigos [6]
Metadatos
Mostrar o rexistro completo do ítemTítulo
Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethersData
2002-06-25Cita bibliográfica
Ruiz, M.; Ojea, V.; Quintela, J. M.; Guillín, J. J. Chem. Commun. 2002, 1600-1601
Resumo
[Abstract] Electrophilic fluorinations of lithiated bis-lactim ethers derived from cyclo-[L-AP4-D-Val] allow a direct access to alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, in enantiomerically pure form and suitable protected for solid-phase peptide synthesis.
Palabras chave
Phosphonate mimetics
Phosphoserine
Phosphothreonine
Electrophilic fluorination
Bis-lactim ethers
Amino acid
Phosphoserine
Phosphothreonine
Electrophilic fluorination
Bis-lactim ethers
Amino acid
Versión do editor
ISSN
1359-7345