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Potential role of sugar transporters in cancer and their relationship with anticancer therapy
(Hindawi, 2010-06-20)
[Abstract] Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. ...
Diverse large HIV-1 non-subtype B clusters are spreading among men who have sex with men in Spain
(Frontiers, 2019-08-03)
[Abstract] In Western Europe, the HIV-1 epidemic among men who have sex with men (MSM) is
dominated by subtype B. However, recently, other genetic forms have been reported to
circulate in this population, as evidenced ...
Social factors and quality of life aspects on frailty syndrome in community-dwelling older adults: the VERISAÚDE study
(BioMed Central, 2018-03-07)
[Abstract]
Background. Frailty is a multidimensional clinical geriatric syndrome that may be reversed in its early stages. Most studies have paid attention to its physical or phenotypic boundaries, however, little is ...
Experimental study and random forest prediction model of microbiome cell surface hydrophobicity
(Elsevier, 2016-11-09)
[Abstract] The cell surface hydrophobicity (CSH) is an assessable physicochemical property used to evaluate the microbial adhesion to the surface of biomaterials, which is an essential step in the microbial biofilm formation ...
Prediction of Nucleoitide Binding Peptides Using Star Graph Topological Índices
(Elsevier, 2015-08-05)
[Abstract] The nucleotide binding proteins are involved in many important cellular processes, such as transmission of genetic information or energy transfer and storage. Therefore, the screening of new peptides for this ...
Multiple biomarker tissue arrays: a computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway
(BioMed Central, 2012-09-01)
[Abstract]
Background. Many studies have demonstrated genetic and environmental factors that lead to renal cell carcinoma (RCC) and that occur during a protracted period of tumourigenesis. It appears suitable to identify ...
Diagnosis, clinical course, and 1-year outcome in patients hospitalized for heart failure with preserved ejection fraction (from the Polish Cohort of the European Society of Cardiology Heart Failure Long-Term Registry)
(Elsevier, 2016)
[Abstract] Compared with heart failure (HF) with reduced ejection fraction (HF-REF), the diagnosis of HF with preserved EF (HF-PEF) is more challenging. The aim of the study was to assess the prevalence of HF-PEF among ...
Mapping chemical structure-activity information of HAART-drug cocktails over complex networks of AIDS epidemiology and socioeconomic data of U.S. counties
(Elsevier, 2015-04-24)
[Abstract] Using computational algorithms to design tailored drug cocktails for highly active antiretroviral therapy (HAART) on specific populations is a goal of major importance for both pharmaceutical industry and public ...
Net-net Auto machine learning (AutoML) prediction of complex ecosystems
(Nature, 2018-08-17)
[Abstract] Biological Ecosystem Networks (BENs) are webs of biological species (nodes) establishing trophic relationships (links). Experimental confirmation of all possible links is difficult and generates a huge volume ...
Effect of ghrelin on glucose-insulin homeostasis: therapeutic implications
(Hindawi, 2010)
[Abstract] Ghrelin is a 28-amino-acid peptide that displays a strong growth hormone- (GH-) releasing activity through the activation of the growth hormone secretagogue receptor (GHSR). The first studies about role of ghrelin ...