• Neuronal Cytotoxicity and Genotoxicity Induced by Zinc Oxide Nanoparticles 

      Valdiglesias, Vanessa; Costa, C.; Kiliç, Gözde; Costa, Solange; Pásaro, Eduardo; Laffon, Blanca; Teixeira, João Paulo (Elsevier, 2013-03-26)
      [Abstract] Zinc oxide nanoparticles (ZnO NPs) are one of the most abundantly used nanomaterials in consumer products and biomedical applications. As a result, human exposure to these NPs is highly frequent and they have ...
    • Nuevos modelos de atención sanitaria para las personas transgénero en el sistema sanitario español: demandas, controversias y reflexiones 

      Gómez-Gil, Esther; Esteva de Antonio, Isabel; Fernández Rodríguez, María; Almaraz Almaraz, Maricruz; Hurtado Murillo, Felipe; Gómez Balaguer, Marcelino; Asenjo Araque, Nuria; Mora Porta, Mireia; Halperin Rabinovich, Irene; Fernández, Rosa; Montejo González, Ángel Luis; Grupo Gidseen (2020)
      [Resumen] La atención sanitaria a las personas transgénero en España se ha establecido de manera progresiva desde 1999, año en que Andalucía crea la primera unidad multidisciplinar para el tratamiento integral de la ...
    • Okadaic Acid Induces Morphological Changes, Apoptosis and Cell Cycle Alterations in Different Human Cell Types 

      Valdiglesias, Vanessa; Laffon, Blanca; Pásaro, Eduardo; Méndez, Josefina (Royal Society of Chemistry (Gran Bretaña), 2011-03-28)
      [Abstract] Okadaic acid (OA) is a marine toxin produced by dinoflagellate species which is frequently accumulated in molluscs usual in the human diet. The exact action mechanism of OA has not been described yet and the ...
    • Okadaic Acid Meet and Greet: An Insight into Detection Methods, Response Strategies and Genotoxic Effects in Marine Invertebrates 

      Prego-Faraldo, María Verónica; Valdiglesias, Vanessa; Méndez, Josefina; Eirín-López, J.M. (Multidisciplinary Digital Publishing Institute, 2013)
      Harmful Algal Blooms (HABs) constitute one of the most important sources of contamination in the oceans, producing high concentrations of potentially harmful biotoxins that are accumulated across the food chains. One such ...
    • Okadaic Acid: More than a Diarrheic Toxin 

      Valdiglesias, Vanessa; Prego-Faraldo, María Verónica; Pásaro, Eduardo; Méndez, Josefina; Laffon, Blanca (Multidisciplinary Digital Publishing Institute, 2013)
      Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be consumed by humans causing alimentary ...
    • Reflexión sobre la implementación de un instrumento de evaluación cognitiva en Terapia Ocupacional : la batería de evaluación cognitiva loewenstein occupational therapy cognitive assessment (LOTCA) 

      Ávila Álvarez, Adriana I.; Viana-Moldes, Inés; Torres-Tobío, Gabriel; López-Cortón-Facal, Ana (COTOGA, 2010-02)
      [Resumen] Este artículo pretende informar y aclarar las dudas, errores de interpretación y necesidades que han aparecido entre los alumnos y profesionales de terapia ocupacional, entre los años 2004 al 2009, en relación ...
    • Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage 

      Valdiglesias, Vanessa; Fernández-Bertólez, Natalia; Lema-Arranz, Carlota; Rodríguez-Fernández, Raquel; Pásaro, Eduardo; Reis, Ana Teresa; Teixeira, João; Costa, C.; Laffon, Blanca (MDPI, 2021-07-27)
      [Abstract] Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue ...
    • Sociedad urbana e inmigración en España : nuevo marco de las relaciones grupales 

      Romay Martínez, José; López-Cortón-Facal, Ana; Gil-Lacruz, Marta (Universidad de Lima, 2012-03-02)
      [Resumen] De ser un país de emigrantes, España se ha convertido en poco tiempo, en un foco importante de inmigrantes que acuden a sus ciudades principales. En épocas de crisis e incertidumbre como la nuestra, a menudo el ...
    • Suitability of Salivary Leucocytes to Assess DNA Repair Ability in Human Biomonitoring Studies by the Challenge-Comet Assay 

      Fernández-Bertólez, Natalia; Lema Arranz, Carlota; Fraga, S.; Teixeira, Joao; Pasaro, Eduardo; Lorenzo-López, Laura; Valdiglesias, Vanessa; Laffon, Blanca (Elsevier, 2022)
      [Abstract] The challenge-comet assay is a simple but effective approach that provides a quantitative and functional determination of DNA repair ability, and allows to monitor the kinetics of repair process. Peripheral blood ...
    • Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells 

      Fernández-Bertólez, Natalia; Brandão, Fátima; Costa, C.; Pásaro, Eduardo; Teixeira, João; Laffon, Blanca; Valdiglesias, Vanessa (2021)
      [Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) ...
    • The hCOMET Project: International Database Comparison of Results with the Comet Assay in Human Biomonitoring. Baseline Frequency of DNA Damage and Effect of Main Confounders 

      Milić, Mirta; Ceppi, Marcello; Bruzzone, Marco; Azqueta, Amaya; Brunborg, Gunnar; Godschalk, Roger; Koppen, Gudrun; Langie, Sabine; Møller, Peter; Alija, Avdulla; Anderson, Diana; Andreoli, Cristina; Asllani, Fisnik; Boutet-Robinet, Elisa; Buschini, Annamaria; Cavallo, Delia; Costa, Solange; Da Silva, Juliana; Del Boˊ, Cristian; Djelić, Ninoslav; Dobrzyńska, Malgorzata; Dvořáková, Monika; Gajski, Goran; Galati, Serena; García Lima, Omar; Giovannelli, Lisa; Goroshinskaya, Irina A.; Grindel, Annemarie; Hernández, Alba; Hernández, Carlos; Holven, Kirsten B.; Ibero-Baraibar, Idoia; Ottestad, Inger; Kadioglu, Ela; Kuznetsova, Elena; Ladeira, Carina; Laffon, Blanca; Lamonaca, Palma; Lebailly, Pierre; Louro, Henriqueta; Mandina Cardoso, Tania; Marcon, Francesca; Marcos, Ricard; Moretti, Massimo; Moretti, Silvia; Najafzadeh, Mojgan; Nemeth, Zsuzsanna; Neri, Monica; Novotna, Bozena; Orlow, Irene; Paduchova, Zuzana; Pastor, Susana; Perdry, Hervé; Spremo-Potparević, Biljana; Ramadhani, Dwi; Riso, Patrizia; Rohr, Paula; Rojas, Emilio; Rossner, Pavel; Sardas, Semra; Silva, Maria João; Sirota, Nikolay; Smolkova, Bozena; Staruchova, Marta; Stetina, Rudolf; Stopper, Helga; Ursini, Cinzia Lucia; Valdiglesias, Vanessa; Valverde, Mahara; Volkovova, Katarina; Wagner, Karl-Heinz; Živković, Lada; Dušinská, Maria; Collins, Andrew R.; Bonassi, Stefano; Teixeira, João; Andrade, Vanessa Moraes de; Bankoglu, Ezgi Eylül; Barančoková, Magdaléna; Pereira, Cristiana; Dimitrijević-Srećković, Vesna; Sáfár, Anna; Surikova, Ekaterina; Vodička, Pavel; Başaran, Nurşen; Costa, C.; Ďuračková, Zdeňka; Kažimírová, Alena; Gützkow, Kristine Bjerve; Ulven, Stine Marie (2021)
      [Abstract] The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification ...
    • The Marine Toxin Okadaic Acid Induces Alterations in the Expression Level of Cancer-Related Genes in Human Neuronal Cells 

      Valdiglesias, Vanessa; Fernández-Tajes, Juan; Méndez, Josefina; Pásaro, Eduardo; Laffon, Blanca (Elsevier, 2013-04-03)
      [Abstract] Okadaic acid (OA) is one of the most common and highly distributed marine toxins. It can be accumulated in several molluscs and other marine organisms and cause acute gastrointestinal symptoms after oral consumption ...
    • The Organic Selenium Compound Selenomethionine Modulates Bleomycin-Induced DNA Damage and Repair in Human Leukocytes 

      Laffon, Blanca; Valdiglesias, Vanessa; Pásaro, Eduardo; Méndez, Josefina (Springer, 2009-05-08)
      [Abstract] The objective of this work was to evaluate the effects of selenomethionine (SeMet) on the induction, repair, and persistence of DNA damage in human leukocytes challenged with bleomycin (BLM). Comet assay was ...