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Prostate cancer and Hedgehog signalling pathway
(Springer, 2007-08-02)
[Abstract] The Hedgehog (Hh) family of intercellular signalling proteins have come to be recognised as key mediators in many fundamental processes in embryonic development. Their activities are central to the growth, ...
Origin of renal cell carcinomas
(Springer, 2008-11-28)
[Abstract] Cancer is a heritable disorder of somatic cells: environment and heredity are both important in the carcinogenic process. The primal force is the “two hits” of Knudson’s hypothesis, which has proved true for ...
Tissue array analysis for the differentiation of gliosis from gliomas
(Spandidos, 2011-03-22)
[Abstract] The aim of this study was to provide a methodology to make a clear distinction between malignant tumors and morphologically similar benign processes, by examining the expression of EGFR, VEGF, HIF1-α, survivin, ...
Expression of Wnt gene family and frizzled receptors in head and neck squamous cell carcinomas
(Spirnger, 2009)
[Abstract] Genes of the Wnt and Frizzled class, expressed in HNSCC tissue and cell lines, have an established role in cell morphogenesis and differentiation, and also they have oncogenic properties. We studied Wnt and Fz ...