Now showing items 1-20 of 37

    • AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients 

      Núñez, Lucía; Marrón Liñares, Grecia Manuela; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Álvarez López, Eloy; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Pombo-Otero, Jorge; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez-Rodríguez, José Manuel (Stanislaw Stepkowski,, 2019-07-23)
      [Abstract] Introduction. One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection (AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and treatment. ...
    • Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report 

      Núñez, Lucía; Crespo-Leiro, María Generosa; Marrón Liñares, Grecia Manuela; Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Hermida-Prieto, Manuel (Via Médica, 2016)
      [Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...
    • Axillary implantation of Impella CP allows early rehabilitation of patients in cardiogenic shock bridged to heart transplantation 

      Couto-Mallón, David; Estévez-Cid, Francisco; Velasco-García, Carlos; Herrera-Noreña, José M.; Iglesias-Gil, Carmen; Solla-Buceta, Miguel; Seoane-Quiroga, L.; Aller-Fernández, V.; Fojón, S.; Balsa-Canto, M.; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Cuenca-Castillo, José J. (Wiley, 2017-05)
    • Body surface area as a prognostic marker in chronic heart failure patients: results from the Heart Failure Registry of the Heart Failure Association of the European Society of Cardiology 

      Zafrir, Barak; Salman, Nabeeh; Crespo-Leiro, María Generosa; Anker, Stefan; Coats, Andrew J.; Ferrari, Roberto; Filippatos, Gerasimos; Maggioni, Aldo P.; Mebazaa, Alexandre; Piepoli, Massimo Francesco; Ruschitzka, Frank; Paniagua-Martín, María J.; Segovia-Cubero, Javier; Laroche, Cecile; Amir, Offer (Wiley, 2016-07-18)
      [Abstract] AIMS: The 'obesity paradox' is consistently observed in patients with heart failure (HF). We investigated the relationship of body surface area (BSA) to mortality and hospitalizations in patients with chronic ...
    • Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance 

      Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)
      [Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ...
    • Circulating miR-181a-5p as a new biomarker for acute cellular rejection in heart transplantation 

      Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)
      [Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...
    • Clinical Characteristics and Long-term outcomes of patients undergoing combined heart-kidney transplantation: a single-center experience 

      López-Sainz, A.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Sánchez-Fernández, G.; Fernández Arias, L.; García-Vieites, M.; Alonso-Hernández, Á.; Rodríguez-Rivera-García, J.J.; Crespo-Leiro, María Generosa (Elsevier, 2015-01-30)
      [Abstract] Background. The purpose of the study was to describe clinical characteristics and long-term survival of patients undergoing combined heart-kidney transplant in a single center. Methods. We conducted a retrospective ...
    • Clinical evaluation of rosuvastatin in heart transplant patients with hypercholesterolemia and therapeutic failure of other statin regimens: short-term and long-term efficacy and safety results 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; Marzoa Rivas, Raquel; Paniagua-Martín, María J.; Barrio-Rodríguez, Alfredo; Naya, Carmen; Blanco-Canosa, Paula; Grille Cancela, Zulaika; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2015-04-23)
      [Abstract] We conducted an observational study of 30 heart transplant recipients with serum low-density lipoprotein cholesterol (LDL-c) >100 mg/dl despite previous statin therapy, who were treated with rosuvastatin 10 mg ...
    • Clinical profile and causes of death according to ejection fraction in patients with heart failure cared for in a specialized Cardiology unit 

      Barge-Caballero, Eduardo; Montero-Fole, B.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Pardo-Martínez, Patricia; Sagastagoitia-Fornie, Marta; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-05-14)
      [Abstract] Background and objective. Patients with heart failure are classified into three phenotypes based on left ventricular ejection fraction. This work aimed to compare the clinical profile, treatment, prognosis, ...
    • Determinants and prognostic value of peak oxygen uptake in the current era of heart failure disease modifying therapy 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Martínez-Ruiz, D.; Fábregas-Casal, R.; Blanco-Canosa, Paula; Naya, Carmen; Riveiro-Rodríguez, C.M.; Grille Cancela, Zulaika; Costa-Grana, C.M.; Pérez-Fernández, R.; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2017-05-01)
    • Determinants of Maximal Oxygen Uptake in Patients With Heart Failure 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Barbeito Caamaño, Cayetana; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pardo-Martínez, Patricia; Grille Cancela, Zulaika; Blanco-Canosa, Paula; García-Pinilla, José Manuel; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-03-27)
      [Abstract] Aims Maximum oxygen uptake (VO₂max) is an essential parameter to assess functional capacity of patients with heart failure (HF). We aimed to identify clinical factors that determine its value, as they have not ...
    • Estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco: ¿un factor pronóstico independiente? 

      Barge-Caballero, Eduardo; Berbeito-Caamaño, Cayetana; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Herrera-Noreña, José M.; Cuenca-Castillo, José J.; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2016-08-31)
      [Resumen] Introducción y objetivos. Analizar la influencia pronóstica del estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco (TC). Métodos. Se realizó un estudio retrospectivo unicéntrico ...
    • Evaluation of humoral immunity profiles to identify heart recipients at risk for development of severe infections: a multicenter prospective study 

      Sarmiento, Elizabeth; Jaramillo, María; Calahorra, Leticia; Fernández-Yáñez, Juan; Gómez-Sánchez, Miguel; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Almenar-Bonet, Luis; Cebrián, Mónica; Rábago, Gregorio; Levy, Beltrán; Segovia-Cubero, Javier; Gómez-Bueno, Manuel; López, Javier; Mirabet, Sonia; Navarro, Joaquín; Rodríguez-Molina, Juan José; Fernández-Cruz, Eduardo; Carbone, Javier (Elsevier, 2017)
      [Abstract] BACKGROUND: New biomarkers are necessary to improve detection of the risk of infection in heart transplantation. We performed a multicenter study to evaluate humoral immunity profiles that could better enable ...
    • Gene expression profiling for monitoring graft rejection in heart transplant recipients 

      Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Hermida-Prieto, Manuel; Castro-Beiras, Alfonso (Elsevier, 2009-08-26)
      [Abstract] Heart transplantation is a life-prolonging therapy for many patients with stage D heart failure and other forms of advanced heart disease. However, graft rejection and/or immunosuppression-related side effects ...
    • Hypotension, acidosis and vasodilation syndrome after heart transplant: incidence, risk factors, and prognosis 

      Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Muñiz, Javier; Vázquez, E.; Tabuyo, T.; Castro-Orjales, M.; Fojón, S.; López, J.M.; Garrido, Iris P.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2003-08-30)
      [Abstract] Background. HAV syndrome, the combination of hypotension, acidosis and vasodilation (HAV), is a serious postoperative complication after heart transplantation (HT). Its etiology and prognosis are poorly ...
    • Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation 

      Suárez-Fuentetaja, Natalia; Domenech-García, Nieves; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Grille Cancela, Zulaika; Pombo-Otero, Jorge; Muñiz, Javier; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier, 2012-11-10)
      [Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...
    • Is Becker dystrophinopathy a contraindication to heart transplant?: experience in a single institution 

      Ascencio-Lemus, Marisol Guadalupe; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Crespo-Leiro, María Generosa (Elsevier, 2018-07-17)
    • Light chain and transthyretin cardiac amyloidosis: Clinical characteristics, natural history and prognostic factors 

      Barge-Caballero, Gonzalo; Vázquez-García, Raquel; Barge-Caballero, Eduardo; Couto-Mallón, David; Paniagua-Martín, María J.; Barriales-Villa, Roberto; Piñón-Esteban, Pablo; Bouzas-Mosquera, Alberto; Pombo-Otero, Jorge; Debén-Ariznavarreta, Guillermo; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-03-13)
      [Abstract] Introduction and objectives. Light-chain amyloidosis (AL-CA) and transthyretin amyloidosis (ATTR-CA) are the most common types of cardiac amyloidosis (CA). We sought to study the clinical characteristics and ...
    • Long-term results of heart transplant in recipients older and younger than 65 years: a comparative study of mortality, rejections, and neoplasia in a cohort of 445 patients 

      Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Marzoa Rivas, Raquel; Piñón-Esteban, Pablo; Rodríguez-Fernández, José Ángel; Hermida, L.F.; Calviño-Santos, Ramón; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2005-12-28)
      [Resumen] Background. Whether being older than 65 years should be considered an absolute counterindication to heart transplant (HT), as it is in some centers, is controversial. In our centre, patients older than 65 years ...
    • Lung cancer after heart transplantation: results from a large multicenter registry 

      Crespo-Leiro, María Generosa; Villa-Arranz, Adolfo; Manito-Lorite, Nicolás; Paniagua-Martín, María J.; Rábago, Gregorio; Almenar-Bonet, Luis; Alonso-Pulpón, Luis; Mirabet, Sonia; Díaz Molina, Beatriz; González-Vílchez, Francisco; Arizón-del-Prado, José M.; Romero-Rodríguez, N.; Delgado-Jiménez, Juan F.; Roig, Eulàlia; Blasco-Peiró, Teresa; Pascual Figal, Domingo A.; De la Fuente-Galán, Luis; Muñiz, Javier (Wiley, 2011-04-26)
      [Abstract] In this study we analyzed Spanish Post-Heart-Transplant Tumour Registry data for adult heart transplantation (HT) patients since 1984. Median post-HT follow-up of 4357 patients was 6.7 years. Lung cancer (mainly ...