Now showing items 1-20 of 47

    • AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients 

      Núñez, Lucía; Marrón Liñares, Grecia Manuela; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Álvarez López, Eloy; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Pombo-Otero, Jorge; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez Rodríguez, José Manuel (Stanislaw Stepkowski,, 2019-07-23)
      [Abstract] Introduction. One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection (AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and treatment. ...
    • Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report 

      Núñez, Lucía; Crespo-Leiro, María Generosa; Marrón Liñares, Grecia Manuela; Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Hermida-Prieto, Manuel (Via Médica, 2016)
      [Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...
    • Axillary implantation of Impella CP allows early rehabilitation of patients in cardiogenic shock bridged to heart transplantation 

      Couto-Mallón, David; Estévez-Cid, Francisco; Velasco-García, Carlos; Herrera-Noreña, José M.; Iglesias-Gil, Carmen; Solla-Buceta, Miguel; Seoane-Quiroga, L.; Aller-Fernández, V.; Fojón, S.; Balsa-Canto, M.; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Cuenca-Castillo, José J. (Wiley, 2017-05)
    • Body surface area as a prognostic marker in chronic heart failure patients: results from the Heart Failure Registry of the Heart Failure Association of the European Society of Cardiology 

      Zafrir, Barak; Salman, Nabeeh; Crespo-Leiro, María Generosa; Anker, Stefan; Coats, Andrew J.; Ferrari, Roberto; Filippatos, Gerasimos; Maggioni, Aldo P.; Mebazaa, Alexandre; Piepoli, Massimo Francesco; Ruschitzka, Frank; Paniagua-Martín, María J.; Segovia-Cubero, Javier; Laroche, Cecile; Amir, Offer (Wiley, 2016-07-18)
      [Abstract] AIMS: The 'obesity paradox' is consistently observed in patients with heart failure (HF). We investigated the relationship of body surface area (BSA) to mortality and hospitalizations in patients with chronic ...
    • Cancer in patients with heart failure: incidence, risk factors and prognostic impact 

      Sagastagoitia-Fornie, Marta; Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Enríquez-Vázquez, Daniel; Blanco-Canosa, Paula; Grille-Cancela, Zulaika; Jiménez-Navarro, Manuel; Muñiz, Javier; Vázquez-Rodríguez, José M.; Crespo-Leiro, María Generosa (Elsevier, 2022-09-16)
      [Abstract] Aims: To assess the incidence of cancer diagnosis and cancer-related mortality in patients with heart failure (HF). Methods: Observational study based in a prospective cohort of patients with HF referred to ...
    • Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance 

      Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)
      [Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ...
    • Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value 

      Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Bayés-Genís, Antoni; Doménech, Nieves; Moreda-Santamaría, Lucía; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Cuenca-Castillo, José J.; Pombo-Otero, Jorge; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2018-11-23)
      [Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...
    • Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation 

      Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)
      [Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ...
    • Clinical Characteristics and Long-term outcomes of patients undergoing combined heart-kidney transplantation: a single-center experience 

      López-Sainz, A.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Sánchez-Fernández, G.; Fernández Arias, L.; García-Vieites, M.; Alonso-Hernández, Á.; Rodríguez-Rivera-García, J.J.; Crespo-Leiro, María Generosa (Elsevier, 2015-01-30)
      [Abstract] Background. The purpose of the study was to describe clinical characteristics and long-term survival of patients undergoing combined heart-kidney transplant in a single center. Methods. We conducted a retrospective ...
    • Clinical evaluation of rosuvastatin in heart transplant patients with hypercholesterolemia and therapeutic failure of other statin regimens: short-term and long-term efficacy and safety results 

      Barge-Caballero, Gonzalo; Barge-Caballero, Eduardo; Marzoa Rivas, Raquel; Paniagua-Martín, María J.; Barrio-Rodríguez, Alfredo; Naya, Carmen; Blanco-Canosa, Paula; Grille Cancela, Zulaika; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2015-04-23)
      [Abstract] We conducted an observational study of 30 heart transplant recipients with serum low-density lipoprotein cholesterol (LDL-c) >100 mg/dl despite previous statin therapy, who were treated with rosuvastatin 10 mg ...
    • Clinical Profile and Causes of Death According to Ejection Fraction in Patients With Heart Failure Cared for in a Specialized Cardiology Unit 

      Barge-Caballero, Eduardo; Montero-Fole, B.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Pardo-Martínez, Patricia; Sagastagoitia-Fornie, Marta; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-05-14)
      [Abstract] Background and objective. Patients with heart failure are classified into three phenotypes based on left ventricular ejection fraction. This work aimed to compare the clinical profile, treatment, prognosis, ...
    • Comparison of predicted and observed mortality in patients with heart failure treated at a specialized unit 

      Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa-Rivas, Raquel; Naya-Leira, Carmen; Riveiro-Rodríguez, Cristina M.; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-01-21)
      [Abstract] Introduction and objectives: To analyze survival in heart failure (HF) patients treated at a specialized unit. Methods: Prospective cohort-based study of HF patients treated at a specialized unit from 2011 ...
    • Determinants and prognostic value of peak oxygen uptake in the current era of heart failure disease modifying therapy 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Martínez-Ruiz, D.; Fábregas-Casal, R.; Blanco-Canosa, Paula; Naya, Carmen; Riveiro-Rodríguez, C.M.; Grille Cancela, Zulaika; Costa-Grana, C.M.; Pérez-Fernández, R.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2017-05-01)
    • Determinants of Maximal Oxygen Uptake in Patients With Heart Failure 

      Roibal-Pravio, J.; Barge-Caballero, Eduardo; Barbeito Caamaño, Cayetana; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pardo-Martínez, Patricia; Grille Cancela, Zulaika; Blanco-Canosa, Paula; García-Pinilla, José Manuel; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley Online Library, 2021-03-27)
      [Abstract] Aims Maximum oxygen uptake (VO₂max) is an essential parameter to assess functional capacity of patients with heart failure (HF). We aimed to identify clinical factors that determine its value, as they have not ...
    • Epidemiological study of tricuspid regurgitation after cardiac transplantation: does it influence survival? 

      López-Vilella, Raquel; Paniagua-Martín, María J.; González-Vílchez, Francisco; Donoso Trenado, Víctor; Barge-Caballero, Eduardo; Sánchez-Lázaro, Ignacio; Aller Fernández, Ana Vanesa; Martínez-Dolz, Luis; Crespo-Leiro, María Generosa; Almenar-Bonet, Luis (Frontiers, 2022-03-21)
      [Abstract] Background: Tricuspid valve disease is the most frequent valvulopathy after heart transplantation (HTx). Evidence for the negative effect of post-transplant tricuspid regurgitation (TR) on survival is contradictory. ...
    • Estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco: ¿un factor pronóstico independiente? 

      Barge-Caballero, Eduardo; Berbeito-Caamaño, Cayetana; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Herrera-Noreña, José M.; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2016-08-31)
      [Resumen] Introducción y objetivos. Analizar la influencia pronóstica del estado serológico frente a Toxoplasma gondii en receptores de trasplante cardiaco (TC). Métodos. Se realizó un estudio retrospectivo unicéntrico ...
    • Evaluation of humoral immunity profiles to identify heart recipients at risk for development of severe infections: a multicenter prospective study 

      Sarmiento, Elizabeth; Jaramillo, María; Calahorra, Leticia; Fernández-Yáñez, Juan; Gómez-Sánchez, Miguel; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Almenar-Bonet, Luis; Cebrián, Mónica; Rábago, Gregorio; Levy, Beltrán; Segovia-Cubero, Javier; Gómez-Bueno, Manuel; López, Javier; Mirabet, Sonia; Navarro, Joaquín; Rodríguez-Molina, Juan José; Fernández-Cruz, Eduardo; Carbone, Javier (Elsevier, 2017)
      [Abstract] BACKGROUND: New biomarkers are necessary to improve detection of the risk of infection in heart transplantation. We performed a multicenter study to evaluate humoral immunity profiles that could better enable ...
    • Gene expression profiling for monitoring graft rejection in heart transplant recipients 

      Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Hermida-Prieto, Manuel; Castro-Beiras, Alfonso (Elsevier, 2009-08-26)
      [Abstract] Heart transplantation is a life-prolonging therapy for many patients with stage D heart failure and other forms of advanced heart disease. However, graft rejection and/or immunosuppression-related side effects ...
    • Hypotension, acidosis and vasodilation syndrome after heart transplant: incidence, risk factors, and prognosis 

      Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Muñiz, Javier; Vázquez, E.; Tabuyo, T.; Castro-Orjales, M.; Fojón, S.; López, J.M.; Garrido, Iris P.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2003-08-30)
      [Abstract] Background. HAV syndrome, the combination of hypotension, acidosis and vasodilation (HAV), is a serious postoperative complication after heart transplantation (HT). Its etiology and prognosis are poorly ...
    • In-Hospital Post-Operative Infection after Heart Transplantation: Epidemiology, Clinical Management, and Outcome 

      Gómez-López, Rocío; Barge-Caballero, Eduardo; Fernández-Ugidos, Paula; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Velasco-García de Sierra, Carlos; Aller-Fernández, Vanesa; Fernández-Arias, Laura; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Mary Ann Liebert, 2020-02-13)
      [Abstract] Background: Infection is a major cause of morbidity and mortality after heart transplantation (HT). Little information about its importance in the immediate post-operative period is available. The aim of this ...