Now showing items 1-5 of 5

    • Analysis of mitochondrial proteins in the surviving myocardium after ischemia identifies mitochondrial pyruvate carrier expression as possible mediator of tissue 

      Fernández Caggiano, Mariana; Prysyazhna, Oleksandra; Barallobre-Barreiro, Javier; Calviño Santos, Ramón; Aldama López, Guillermo; Crespo-Leiro, María Generosa; Eaton, Philip; Doménech, Nieves (American Society for Biochemistry and Molecular Biology, 2016-01-01)
    • Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling 

      Barallobre-Barreiro, Javier; Radovits, Tamás; Fava, Marika; Mayr, Ursula; Lin, Wen-Yu; Ermolaeva, Elizaveta; Martínez-López, Diego; Lindberg, Eric L.; Duregotti, Elisa; Daróczi, László; Hasman, Maria; Schmidt, Lukas E.; Singh, Bhawana; Lu, Ruifang; Baig, Ferheen; Siedlar, Aleksandra Malgorzata; Cuello, Friederike; Catiborg, Norman; Theofilatos, Konstantinos; Shah, Ajay M.; Crespo-Leiro, María Generosa; Doménech, Nieves; Hübner, Norbert; Merkely, Béla; Mayr, Manuel (American Heart Association, 2021-11-22)
      [Abstract] Background: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disintegrin and metalloproteinase ...
    • Mitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in Spanish population 

      Fernández Caggiano, Mariana; Barallobre-Barreiro, Javier; Rego-Pérez, Ignacio; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Grille Cancela, Zulaika; Blanco García, Francisco J; Doménech, Nieves (Elsevier, 2013-03-23)
      [Abstract] Idiopathic dilated cardiomyopathy (IDC) is a structural heart disease with strong genetic background. The different single nucleotide polymorphisms (SNPs) that constitute mitochondrial haplogroups could play an ...
    • Mitochondrial haplogroups H and J: risk and protective factors for ischemic cardiomyopathy 

      Fernández Caggiano, Mariana; Barallobre-Barreiro, Javier; Rego-Pérez, Ignacio; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Grille Cancela, Zulaika; Blanco García, Francisco J; Doménech, Nieves (PLoS, 2012-08-28)
      [Abstract] Background. Since mitochondria are the principal source of reactive oxygen species (ROS), these organelles may play an important role in ischemic cardiomyopathy (IC) development. The mitochondrial genome may ...
    • SERCA2a protein levels are unaltered in human heart failure 

      Ragone, Isabella; Barallobre-Barreiro, Javier; Takov, Kaloyan; Theofilatos, Konstantinos; Yin, Xiaoke; Schmidt, Lukas Emanuel; Doménech, Nieves; Crespo-Leiro, María Generosa; van der Voorn, Stephanie M.; Vink, Aryan; van Veen, Toon A.B.; Bödör, Csaba; Merkely, Béla; Radovits, Tamás; Mayr, Manuel (American Heart Association (AHA), 2023-08-14)