• A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype 

      Quelle Regaldie, Ana; Folgueira, Mónica; Yáñez, Julián; Sobrido Cameán, Daniel; Alba-González, Anabel; Barreiro-Iglesias, Antón; Sobrido, María-Jesús; Sánchez Piñón, Laura (MDPI, 2022)
      [Abstract] NOP56 belongs to a C/D box small nucleolar ribonucleoprotein complex that is in charge of cleavage and modification of precursor ribosomal RNAs and assembly of the 60S ribosomal subunit. An intronic expansion ...
    • Distribution of Neurogranin-Like Immunoreactivity in the Brain and Sensory Organs of the Adult Zebrafish 

      Alba-González, Anabel; Folgueira, Mónica; Castro, Antonio; Anadón, Ramón; Yáñez, Julián (Wiley, 2022-01-11)
      [Abstract] We studied the expression of neurogranin in the brain and some sensory organs (barbel taste buds, olfactory organs, and retina) of adult zebrafish. Database analysis shows zebrafish has two paralog neurogranin ...
    • Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos 

      Valdiglesias, Vanessa; Alba-González, Anabel; Fernández-Bertólez, Natalia; Touzani, Assia; Ramos-Pan, Lucía; Reis, Ana Teresa; Moreda-Piñeiro, Jorge; Yáñez, Julián; Laffon, Blanca; Folgueira, Mónica (MDPI, 2023-08-01)
      [Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ...
    • Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Teixeira, Ricardo Gonçalves; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Alba-González, Anabel; Salamini-Montemurri, Martín; Pech-Puch, Dawrin; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2021-02-11)
      [Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...
    • Neurogranin-Like Immunoreactivity in the Zebrafish Brain During Development 

      Alba-González, Anabel; Yáñez, Julián; Anadón, Ramón; Folgueira, Mónica (Springer Nature, 2022-08-26)
      [Abstract] Neurogranin (Nrgn) is a neural protein that is enriched in the cerebral cortex and is involved in synaptic plasticity via its interaction with calmodulin. Recently we reported its expression in the brain of the ...