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ANN multiscale model of anti-HIV Drugs activity vs AIDS prevalence in the US at county level based on information indices of molecular graphs and social networks
(American Chemical Society, 2014)
[Abstract] This work is aimed at describing the workflow for a methodology that combines chemoinformatics and pharmacoepidemiology methods and at reporting the first predictive model developed with this methodology. The ...
Update on hepatitis C virus resistance to direct-acting antiviral agents
(Elsevier, 2014-06-06)
[Abstract] Resistance to direct-acting antiviral (DAA) agents against hepatitis C virus (HCV) infection is driven by the selection of mutations at different positions in the NS3 protease, NS5B polymerase and NS5A proteins. ...
Chronic renal dysfunction in maintenance heart transplant patients: the ICEBERG study
(Elsevier, 2014-02-05)
[Abstract] Chronic renal dysfunction (CRD) is a major complication after heart transplantation. We sought to describe the renal function over time, to assess the risk factors associated with CRD development, and to evaluate ...
Assessing mouse alternatives to access to computer: a case study of a user with cerebral palsy
(Taylor & Francis para RESNA, 2014)
[Abstract] The purpose of this study is to describe the process of assessment of three assistive devices to meet the needs of a woman with cerebral palsy (CP) in order to provide her with computer access and use. The user ...
Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells
(BioMed Central, 2014-07-10)
[Abstract]
Background. Vinflunine (VFL) is a microtubule-targeting drug that suppresses microtubule dynamics, showing anti-metastatic properties both in vitro and in living cancer cells. An increasing body of evidence ...
Molecular characterization of HIV-1 infection in Northwest Spain (2009–2013): investigation of the subtype F outbreak
(Elsevier, 2014-12-16)
[Abstract] Background. HIV-1 subtype B is the predominant one in European regions several, while other subtypes and recombinants are also circulating with high prevalence. A sub-epidemic of subtype F with specific ...