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Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis
(Multidisciplinary Digital Publishing Institute, 2016)
Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs). Although the genotoxic and cytotoxic responses to OA ...
Okadaic Acid: More than a Diarrheic Toxin
(Multidisciplinary Digital Publishing Institute, 2013)
Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be consumed by humans causing alimentary ...
Applicability of EU(7)-PIM criteria in cross-national studies in European countries
(2019)
[Abstract] Background: The European Union (EU)(7)-PIM (potentially inappropriate medication) list
presents the most comprehensive and up-to-date tool for evaluation of PIM prescribing in
Europe; however, several ...
The hCOMET Project: International Database Comparison of Results with the Comet Assay in Human Biomonitoring. Baseline Frequency of DNA Damage and Effect of Main Confounders
(2021)
[Abstract] The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification ...
Minimum Information for Reporting on the Comet Assay (MIRCA): Recommendations for Describing Comet Assay Procedures and Results
(2020)
[Abstract] The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental ...
“Micronuclei and Disease” special issue: Aims, scope, and synthesis of outcomes
(2021)
[Abastract] The purpose of the “Micronuclei and Disease” special issue (SI) is to: (i) Determine the level of evidence for association of micronuclei (MN), a biomarker of numerical and structural chromosomal aberrations, ...
Neuronal Cytotoxicity and Genotoxicity Induced by Zinc Oxide Nanoparticles
(Elsevier, 2013-03-26)
[Abstract] Zinc oxide nanoparticles (ZnO NPs) are one of the most abundantly used nanomaterials in consumer products and biomedical applications. As a result, human exposure to these NPs is highly frequent and they have ...
Identification of Differentially Expressed Genes in SHSY5Y Cells Exposed to Okadaic Acid by Suppression Subtractive Hybridization
(Springer Nature, 2012-01-27)
[Abstract] Background: Okadaic acid (OA), a toxin produced by several dinoflagellate species is responsible for frequent food poisonings associated to shellfish consumption. Although several studies have documented the OA ...
The Marine Toxin Okadaic Acid Induces Alterations in the Expression Level of Cancer-Related Genes in Human Neuronal Cells
(Elsevier, 2013-04-03)
[Abstract] Okadaic acid (OA) is one of the most common and highly distributed marine toxins. It can be accumulated in several molluscs and other marine organisms and cause acute gastrointestinal symptoms after oral consumption ...
Comparative Study on Effects of Two Different Types of Titanium Dioxide Nanoparticles on Human Neuronal Cells
(Elsevier, 2013-04-15)
[Abstract] Titanium dioxide (TiO2) are among most frequently used nanoparticles (NPs). They are present in a variety of consumer products, including food industry in which they are employed as an additive. The potential ...