• There is something you must see: breaking down the remission concept in rheumatoid arthritis from a rheumatologist's perspective 

      Acebes, Carlos; Andreu, José Luis; Balsa, Alejandro; Batlle, Enrique; De-Toro, Javier; García Llorente, Francisco; Hernández Miguel, María Victoria; Fernández-Gutiérrez, Benjamín; Hidalgo-Calleja, Cristina; Mayordomo, Lucía; Naredo, Esperanza; Narváez, Javier; Fernández Ortiz, Ana María; Pablos, José L.; Pérez-Sandoval, Trinidad; Rodríguez-Lozano, Carlos; Sánchez-Pernaute, Olga; Usón, Jacqueline; Negrón, José Bernardo; Loza, Estíbaliz; Carmona, Loreto; Gómez Castro, Susana; Montoro Álvarez, María (Clinical and Experimental Rheumatology, 2020-01)
      [Abstract] Objectives: To explore the remission concept in rheumatoid arthritis (RA) and the implications of the existing definitions when applied to clinical practice among rheumatologists with different profiles. Methods: ...
    • Tips and Tricks for Successfully Culturing and Adapting Human Induced Pluripotent Stem Cells [Protocol] 

      Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Piñeiro-Ramil, María; Rodríguez-Fernández, Silvia; López-Baltar, Isidoro; Fuentes Boquete, Isaac Manuel; Blanco García, Francisco J; Díaz-Prado, Silvia (Cell Press, 2021-12)
      [Abstract] Reprogramming somatic cells toward pluripotency became possible over a decade ago. Since then, induced pluripotent stem cells (iPSCs) have served as a versatile and powerful tool not only for basic research but ...
    • Tissue array analysis for the differentiation of gliosis from gliomas 

      Medina Villaamil, Vanessa; Álvarez García, A.; Aparicio Gallego, Guadalupe; Díaz-Prado, Silvia; Rivas López, A.; Santamarina, Isabel; Valladares-Ayerbes, Manuel; Antón-Aparicio, Luis M. (Spandidos, 2011-03-22)
      [Abstract] The aim of this study was to provide a methodology to make a clear distinction between malignant tumors and morphologically similar benign processes, by examining the expression of EGFR, VEGF, HIF1-α, survivin, ...
    • Tratamiento de lesiones del cartílago articular con terapia celular 

      Fuentes Boquete, Isaac Manuel; Arufe, M.C.; Díaz-Prado, Silvia; Hermida Gómez, Tamara; De-Toro, Javier; Blanco García, Francisco J (Elsevier, 2008-11-13)
      [Resumen] Las lesiones del cartílago articular que no afectan a la integridad del hueso subcondral no se reparan espontáneamente. El carácter asintomático de estas lesiones propicia la progresiva degeneración articular y ...
    • Umbilical Cord as a Mesenchymal Stem Cell Source for Treating Joint Pathologies 

      Arufe, M.C.; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Baishideng, 2011-06-18)
      [Abstract] Articular cartilage disorders and injuries often result in life-long chronic pain and compromised quality of life. Regrettably, the regeneration of articular cartilage is a continuing challenge for biomedical ...
    • Usefulness of mesenchymal cell lines for bone and cartilage regeneration research 

      Piñeiro-Ramil, María; Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Rodríguez-Fernández, Silvia; Fuentes Boquete, Isaac Manuel; Blanco García, Francisco J; Díaz-Prado, Silvia (MDPI, 2019-12-13)
      [Abstract] The unavailability of sufficient numbers of human primary cells is a major roadblock for in vitro repair of bone and/or cartilage, and for performing disease modelling experiments. Immortalized mesenchymal ...
    • Valor pronóstico de la resonancia magnética precoz en la morbilidad y mortalidad de la lesión medular traumática 

      Mora-Boga, Rubén; Vázquez-Muíños, Olalla; Pértega-Díaz, Sonia; Meijide-Faílde, Rosa; Rodríguez-Sotillo, Antonio; Ferreiro-Velasco, María Elena; Salvador-de-la-Barrera, S.; Montoto Marqués, Antonio (Elsevier, 2022-02-12)
      [Resumen] Objetivo. Valorar en individuos con lesión medular traumática (LMT) la relación entre la mortalidad y la necesidad de UCI y las alteraciones objetivadas mediante resonancia magnética (RM) precoz, analizando ...
    • Versatility of induced Pluripotent Stem Cells (iPSCs) for improving the knowledge on musculoskeletal diseases 

      Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Piñeiro-Ramil, María; Rodríguez-Fernández, Silvia; Fuentes Boquete, Isaac Manuel; Blanco García, Francisco J; Díaz-Prado, Silvia (MDPI, 2020-08-25)
      [Abstract] Induced pluripotent stem cells (iPSCs) represent an unlimited source of pluripotent cells capable of di erentiating into any cell type of the body. Several studies have demonstrated the valuable use of iPSCs ...
    • Wnt signalling and cancer stem cells 

      Espada, Jesús; Calvo, Moisés B.; Díaz-Prado, Silvia; Medina, Vanessa (Springer, 2009-07-15)
      [Abstract] Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment of cell fates and proper tissue patterning during embryo development and for the regulation of tissue homeostasis and ...