SynNER: Syntax-infused Named Entity Recognition in the Biomedical Domain

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Muhammad Imran, Olga Zamaraeva, Carlos Gómez-Rodríguez, SynNER: syntax-infused named entity recognition in the biomedical domain, JAMIA Open, Volume 9, Issue 1, February 2026, ooaf149, https://doi.org/10.1093/jamiaopen/ooaf149

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[Abstract]: Named Entity Recognition (NER) is a technology that helps computers automatically find and classify important terms in text, such as names of diseases, drugs, or medical procedures. This is especially valuable in the biomedical field, where researchers and clinicians need to process large volumes of text from scientific articles, clinical notes, or patient records. In this work, we present SynNER, a system that improves the accuracy of NER by teaching computers to pay attention not only to the words themselves, but also to syntax, ie, the internal structure of sentences. For example, recognizing how words are connected in a sentence (which parts of the sentence are subjects, objects or modifiers) can make it easier to correctly identify medical terms, even when they appear in complex contexts. We tested our method on five different collections of biomedical texts. The results showed that incorporating grammatical knowledge significantly boosted accuracy. Our SynNER system outperformed previous state-of-the-art methods on three of the five datasets. Our results show that using syntax can help researchers and healthcare professionals more reliably and quickly extract vital information from a vast amount of text, which could ultimately help improve biomedical research and clinical decision support tools.

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Financiado para publicación en acceso aberto: Universidade da Coruña/CISUG The code and other resources developed for this work are available in our GitHub repository at: https://github.com/chimran135/SynNER. The datasets used in this study are publicly available from third-party sources. The MTSamples and VAERS datasets can be downloaded from: https://github.com/BIDS-Xu-Lab/Clinical_Entity_Recognition_Using_GPT_models. The NCBI-Disease, BC2GM, and JNLPBA datasets can be downloaded from: https://github.com/cambridgeltl/MTL-Bioinformatics-2016. Supplementary material is available at JAMIA Open online

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Attribution 4.0 International
Attribution 4.0 International

Except where otherwise noted, this item's license is described as Attribution 4.0 International