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Identification of Regulatory Mechanisms Driving Acquired Resistance to Olaparib in Ovarian Cancer

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FernandezLozano_Carlos_2026_Identification_of_Regulatory_Mechanisms.pdf (2.56 MB)

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URI: https://hdl.handle.net/2183/49155
DOI: 10.1002/1878-0261.70318

Publication date

2026

Authors

Alonso-Pozo, Alicia

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Bibliographic citation

A. Alonso-Pozo, C. Fernández-Lozano, and J. Liñares-Blanco, "Identification of Regulatory Mechanisms Driving Acquired Resistance to Olaparib in Ovarian Cancer", Abstract EACR26-1361, Molecular Oncology 20 (Suppl. 1), August 2026, ISSN 1878-0261, https://doi.org/10.1002/1878-0261.70318

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Abstract

[Abstract]: This study reconstructs single-cell differentiation trajectories and infers transcription factor activity in high-grade serous ovarian cancer to identify key regulatory mechanisms driving the transition from olaparib-sensitive to resistant cellular states.

Description

Abstract do poster presentado en: Annual Congress of the European Association for Cancer Research (EACR 2026): Innovative Cancer Science, 8-11 June 2026, Budapest, Hungary. Abstracts do congreso en: https://febs.onlinelibrary.wiley.com/doi/epdf/10.1002/1878-0261.70318. Póster dispoñible en: https://hdl.handle.net/2183/49160.

Keywords

Ovarian cancer Olaparib resistance Transcription factors

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Attribution 4.0 International

Except where otherwise noted, this item's license is described as Attribution 4.0 International