Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethers

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UDC.coleccionInvestigaciónes_ES
UDC.departamentoQuímicaes_ES
UDC.grupoInvSíntese Asimétricaes_ES
dc.contributor.authorRuiz, María
dc.contributor.authorOjea, Vicente
dc.contributor.authorQuintela López, José María
dc.contributor.authorGuillín, Juan José
dc.date.accessioned2005-12-19T15:24:03Z
dc.date.available2005-12-19T15:24:03Z
dc.date.issued2002-06-25
dc.description.abstract[Abstract] Electrophilic fluorinations of lithiated bis-lactim ethers derived from cyclo-[L-AP4-D-Val] allow a direct access to alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, in enantiomerically pure form and suitable protected for solid-phase peptide synthesis.es_ES
dc.description.sponsorshipXunta de Galicia; PDGIT00PXI10305PRes_ES
dc.description.sponsorshipMinisterio de Ciencia y Tecnología; BQU2000-0236
dc.format.mimetypeapplication/pdf
dc.format.mimetypeapplication/pdf
dc.identifier.citationRuiz, M.; Ojea, V.; Quintela, J. M.; Guillín, J. J. Chem. Commun. 2002, 1600-1601es_ES
dc.identifier.doi10.1039/B204093J
dc.identifier.issn1359-7345
dc.identifier.urihttp://hdl.handle.net/2183/442
dc.language.isoenges_ES
dc.publisherThe Royal Society of Chemistryes_ES
dc.relation.urihttps://doi.org/10.1039/B204093Jes_ES
dc.rights.accessRightsopen accesses_ES
dc.subjectPhosphonate mimeticses_ES
dc.subjectPhosphoserinees_ES
dc.subjectPhosphothreoninees_ES
dc.subjectElectrophilic fluorinationes_ES
dc.subjectBis-lactim etherses_ES
dc.subjectAmino acides_ES
dc.titleStereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim etherses_ES
dc.typejournal articlees_ES
dspace.entity.typePublication
relation.isAuthorOfPublication51cb91d3-79ab-444d-a358-e798775f3f54
relation.isAuthorOfPublication5cf715bc-5c4a-440d-a9be-a0d501b76a1b
relation.isAuthorOfPublicationdf6ad047-6454-4290-be79-ba9d5eed11ea
relation.isAuthorOfPublication.latestForDiscovery51cb91d3-79ab-444d-a358-e798775f3f54

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