Accelerating water exchange in GdIII–DO3A-derivatives by favouring the dissociative mechanism through hydrogen bonding

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UDC.coleccionInvestigaciónes_ES
UDC.departamentoQuímicaes_ES
UDC.endPage516es_ES
UDC.grupoInvReactividade Química e Fotorreactividade (REACT!)es_ES
UDC.issue4es_ES
UDC.journalTitleChemical Communicationses_ES
UDC.startPage513es_ES
UDC.volume55es_ES
dc.contributor.authorLeone, Loredana
dc.contributor.authorEsteban-Gómez, David
dc.contributor.authorPlatas-Iglesias, Carlos
dc.contributor.authorMilanesio, Marco
dc.contributor.authorTei, Lorenzo
dc.date.accessioned2022-03-18T13:07:00Z
dc.date.available2022-03-18T13:07:00Z
dc.date.issued2018-12-10
dc.description.abstract[Abstract] The GdIII-complexes of DO3A-acetophenone and ortho- or para- hydroxyacetophenone ligands have been investigated to assess the effect of the presence of a phenol group on the relaxivity and on the water exchange rate of these potential MRI contrast agents. H-Bonding between the ortho-phenol(ate) groups and the water molecules involved in the dissociative exchange mechanism is shown to speed up the water exchange rate by stabilizing the eight-coordinate transition state.es_ES
dc.description.sponsorshipThis work was carried out under the EU COST Action CA15209 "European Network on NMR Relaxometry". The authors thank Centro de Supercomputación de Galicia (CESGA) for providing the computer facilitieses_ES
dc.identifier.citationL. Leone, D. Esteban-Gómez, C. Platas-Iglesias, M. Milanesio and L. Tei, Accelerating water exchange in Gd III -DO3A-derivatives by favouring the dissociative mechanism through hydrogen bonding, Chem. Commun., 2019, 55, 513–516. DOI: 10.1039/C8CC08556K.es_ES
dc.identifier.issn1364-548X
dc.identifier.urihttp://hdl.handle.net/2183/30064
dc.language.isoenges_ES
dc.publisherRoyal Society of Chemistryes_ES
dc.relation.urihttps://doi.org/10.1039/C8CC08556Kes_ES
dc.rights.accessRightsopen accesses_ES
dc.titleAccelerating water exchange in GdIII–DO3A-derivatives by favouring the dissociative mechanism through hydrogen bondinges_ES
dc.typejournal articlees_ES
dspace.entity.typePublication
relation.isAuthorOfPublicationf30c18a2-108e-44d6-a7d2-b3b4e378509b
relation.isAuthorOfPublication8bb35ae5-5c53-4d41-87b8-949a82445202
relation.isAuthorOfPublication.latestForDiscoveryf30c18a2-108e-44d6-a7d2-b3b4e378509b

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