Listar por autor "Castro-Beiras, Alfonso"
Mostrando ítems 1-20 de 29
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A MicroRNA transcription factor blueprint for early atrial arrhytmogenic remodeling
Torrado, Mario; Franco, Diego; Lozano-Belasco, Estefanía; Hernández-Torres, Francisco; Calviño-Santos, Ramón; Aldama López, Guillermo; Centeno, Alberto; Castro-Beiras, Alfonso; Mikhailov, Alexander T. (Hindawi, 2015)[Abstract] Spontaneous self-terminating atrial fibrillation (AF) is one of the most common heart rhythm disorders, yet the regulatory molecular mechanisms underlying this syndrome are rather unclear. MicroRNA (miRNA) ... -
Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance
Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)[Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ... -
Differences in outcome of heart failure with preserved or depressed systolic function in patients older than 70 years who receive beta blockers
Anguita, Manuel; Castillo, Juan C.; Ruiz, Martín; Castillo, Francisco; Jiménez-Navarro, Manuel; Crespo-Leiro, María Generosa; Alonso-Pulpón, Luis; Teresa Galván, Eduardo de; Castro-Beiras, Alfonso; Roig, Eulàlia; Artigas, Remei; Zapata, Antonio; López-de-Ullibarri, Ignacio; Muñiz, Javier (Elsevier, 2011-10-14)[Abstract] Introduction and objectives. Most studies have shown that prognosis of heart failure with preserved systolic function is as poor as that of heart failure with depressed systolic function, although these results ... -
Effect of a simple educational program for physicians on adherence to secondary prevention measures after discharge following acute coronary syndrome: the CAM project
Muñiz, Javier; Gómez Doblas, Juan José; Santiago-Pérez, M.I.; Teresa Galván, Eduardo de; Cruz Fernández, José María; Castro-Beiras, Alfonso (Elsevier, 2004)[Abstract] Introduction and objectives. Adherence to established guidelines for patients discharged from the hospital after acute coronary syndrome is known to be suboptimal. The aim of this study was to assess the efficacy ... -
Effect of a training program for primary care physicians on the optimization of beta-blocker treatment in elderly patients with heart failure
Anguita, Manuel; Jiménez-Navarro, Manuel; Crespo-Leiro, María Generosa; Alonso-Pulpón, Luis; Teresa Galván, Eduardo de; Castro-Beiras, Alfonso; Roig, Eulàlia; Artigas, Remei; Zapata, Antonio; López-de-Ullibarri, Ignacio; Muñiz, Javier (Elsevier, 2010)[Abstract] Introduction and objectives. Underuse of beta-blockers may contribute to elevated mortality in chronic heart failure. The aim of this study was to determine whether a specific interventional training program for ... -
Ensayo clínico aleatorizado y controlado para valorar una intervención por una unidad de hospitalización domiciliaria en la reducción de reingresos y muerte en pacientes dados de alta del hospital tras un ingreso por insuficiencia cardiaca
Aldamiz-Echevarría Iraúrgui, Begoña; Muñiz, Javier; Rodríguez-Fernández, José Ángel; Vidán-Martínez, Luciano; Silva-César, Miguel; Lamelo-Alfonsín, Fernando; Díaz-Díaz, José Luis; Ramos-Polledo, Vicente; Castro-Beiras, Alfonso (Elsevier, 2007-09)[Resumen] Introducción y objetivos. Evaluar la eficacia de una intervención de educación en pacientes con insuficiencia cardiaca (IC) realizada por hospitalización a domicilio. Métodos. Ensayo clínico aleatorizado y ... -
Familial Dilated Cardiomyopathy and Isolated Left Ventricular Noncompaction Associated With Lamin A/C Gene Mutations
Hermida-Prieto, Manuel; Monserrat, Lorenzo; Castro-Beiras, Alfonso; Laredo, Rafael; Soler Fernández, Rafaela; Peteiro-Vázquez, Jesús; Rodríguez, Esther; Bouzas-Zubeldia, Beatriz; Álvarez-García, Nemesio; Muñiz, Javier; Crespo-Leiro, María Generosa (Elsevier, 2004-06-23)[Abstract] LMNA mutations have been associated with familial or sporadic dilated cardiomyopathy (DC), with or without conduction system disease. We studied the LMNA gene in 67 consecutive patients with DC (18 had familial ... -
Gene expression profiling for monitoring graft rejection in heart transplant recipients
Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Hermida-Prieto, Manuel; Castro-Beiras, Alfonso (Elsevier, 2009-08-26)[Abstract] Heart transplantation is a life-prolonging therapy for many patients with stage D heart failure and other forms of advanced heart disease. However, graft rejection and/or immunosuppression-related side effects ... -
Hypotension, acidosis and vasodilation syndrome after heart transplant: incidence, risk factors, and prognosis
Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Muñiz, Javier; Vázquez, E.; Tabuyo, T.; Castro-Orjales, M.; Fojón, S.; López, J.M.; Garrido, Iris P.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2003-08-30)[Abstract] Background. HAV syndrome, the combination of hypotension, acidosis and vasodilation (HAV), is a serious postoperative complication after heart transplantation (HT). Its etiology and prognosis are poorly ... -
Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
Suárez-Fuentetaja, Natalia; Doménech, Nieves; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Grille Cancela, Zulaika; Pombo-Otero, Jorge; Muñiz, Javier; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier, 2012-11-10)[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ... -
Insuficiencia cardiaca en España: epidemiología e importancia del grado de adecuación a las guías de práctica clínica
Muñiz, Javier; Crespo-Leiro, María Generosa; Castro-Beiras, Alfonso (Elsevier, 2006)[Resumen] En el presente artículo se abordan aspectos de la magnitud de la insuficiencia cardiaca, con especial mención a la carga que supone la enfermedad en nuestro medio. Se discuten, asimismo, los problemas para estimar ... -
Long-term results of heart transplant in recipients older and younger than 65 years: a comparative study of mortality, rejections, and neoplasia in a cohort of 445 patients
Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Marzoa Rivas, Raquel; Piñón-Esteban, Pablo; Rodríguez-Fernández, José Ángel; Hermida, L.F.; Calviño-Santos, Ramón; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2005-12-28)[Resumen] Background. Whether being older than 65 years should be considered an absolute counterindication to heart transplant (HT), as it is in some centers, is controversial. In our centre, patients older than 65 years ... -
Microchimerism after heart transplantation: prevalence, predisposing factors, natural history, and prognosis
Crespo-Leiro, María Generosa; Hermida-Prieto, Manuel; Rodríguez-Fernández, José Ángel; Muñiz, Javier; Barral, S.; Paniagua-Martín, María J.; Hermida, L.F.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2002-04-10) -
Organization of heart failure care in Spain: characteristics of heart failure units
Castro-Beiras, Alfonso; Anguita, Manuel; Comín, Josep; Vázquez Rodríguez, José Manuel; Frutos, Trinidad de; Muñiz, Javier (Elsevier, 2015-05-08) -
Pitx2c is reactivated in the failing myocardium and stimulates Myf5 expression in cultured cardiomyocytes
Torrado, Mario; Franco, Diego; Hernández-Torres, Francisco; Crespo-Leiro, María Generosa; Iglesias-Gil, Carmen; Castro-Beiras, Alfonso; Mikhailov, Alexander T. (PLoS, 2014-03-04)[Abstract] Background. Pitx2 (paired-like homeodomain 2 transcription factor) is crucial for heart development, but its role in heart failure (HF) remains uncertain. The present study lays the groundwork implicating Pitx2 ... -
Prevalence, etiology, and outcome of catheterization laboratory false alarms in patients with suspected ST-elevation myocardial infarction
Barge-Caballero, Eduardo; Vázquez Rodríguez, José Manuel; Estévez-Loureiro, Rodrigo; Barge-Caballero, Gonzalo; Rodríguez-Vilela, Alejandro; Calviño-Santos, Ramón; Salgado-Fernández, Jorge; Aldama López, Guillermo; Piñón-Esteban, Pablo; Campo-Pérez, Rosa; Rodríguez-Fernández, José Ángel; Vázquez-González, Nicolás; Muñiz, Javier; Castro-Beiras, Alfonso (Elsevier, 2010)[Abstract] Introduction and objectives. To investigate the prevalence, causes and outcome of catheterization laboratory false alarms (CLFAs) in a regional primary angioplasty network. Methods. A prospective registry of ... -
Prevalencia, causas y pronóstico de las «falsas alarmas» al laboratorio de hemodinámica en pacientes con sospecha de infarto de miocardio con elevación del segmento ST
Barge-Caballero, Eduardo; Vázquez Rodríguez, José Manuel; Estévez-Loureiro, Rodrigo; Barge-Caballero, Gonzalo; Rodríguez-Vilela, Alejandro; Calviño-Santos, Ramón; Salgado-Fernández, Jorge; Aldama López, Guillermo; Piñón-Esteban, Pablo; Campo-Pérez, Rosa; Rodríguez-Fernández, José Ángel; Vázquez-González, Nicolás; Muñiz, Javier; Castro-Beiras, Alfonso (Sociedad Española de Cardiología, 2010)[Resumen] Introducción y objetivos. Determinar prevalencia, causas y pronóstico de las «falsas alarmas» al laboratorio de hemodinámica (FALH) en una red regional de angioplastia primaria. Métodos. Registro prospectivo de ... -
Prognostic significance of heart rate and its long-term trend in cardiac transplant patients
Barge-Caballero, Eduardo; Jiménez-López, Jesús; Chávez-Leal, Sergio; Barge-Caballero, Gonzalo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Cuenca-Castillo, José J.; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier para Sociedad Española de Cardiología, 2015-04-11)[Abstract] Introduction and objectives. The aim of the present study was to examine the prognostic significance of heart rate and its trend in heart transplantation. Methods. This observational study enrolled 170 patients ... -
Prognostic Value of Treadmill Exercise Echocardiography
Peteiro-Vázquez, Jesús; Monserrat, Lorenzo; Mariñas-Dávila, Javier; Garrido, Iris P.; Bouzas-Caamaño, María; Muñiz, Javier; Bouzas-Mosquera, Alberto; Bouzas-Zubeldia, Beatriz; Álvarez-García, Nemesio; Castro-Beiras, Alfonso (Elsevier, 2005)[Abstract] Introduction and objectives. Exercise echocardiography (EE) is useful for diagnosing coronary disease, but little is known about its value for risk stratification. We aimed to determine: a) whether data from EE ... -
Quinolone-related Achilles tendinopathy in heart transplant patients: incidence and risk factors
Barge-Caballero, Eduardo; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Bouzas-Mosquera, Alberto; Piñón-Esteban, Pablo; Marzoa Rivas, Raquel; Pazos-López, Pablo; Cursack, Guillermo C.; Cuenca-Castillo, José J.; Castro-Beiras, Alfonso (Elsevier, 2008-01-08)[Abstract] Background. A high incidence of Achilles tendinopathy—tendinitis or rupture—has been observed after quinolone treatment in lung and kidney transplant patients. In the absence of relevant published data, we aimed ...