Listar por autor "Jiménez-Fonseca, Paula"
Mostrando ítems 1-3 de 3
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Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer
Aparicio Gallego, Guadalupe; Díaz-Prado, Silvia; Jiménez-Fonseca, Paula; García Campelo, Rosario; Casinello Espinosa, J.; Antón-Aparicio, Luis M. (Springer, 2007-12-15)[Abstract] Epidemiological studies provided the first evidence that COX may be involved in the pathogenesis of cancer. In the process of carcinogenesis and in the route of intracellular signalling during carcinogenesis, ... -
Evaluation of the efficacy and safety of lanreotide in combination with targeted therapies in patients with neuroendocrine tumours in clinical practice: a retrospective cross-sectional analysis
Capdevila, Jaume; Sevilla, Isabel; Alonso, Vicente; Antón-Aparicio, Luis M.; Jiménez-Fonseca, Paula; Grande, Enrique; Reina, Juan José; Manzano, José Luis; Alonso Lájara, Juan Domingo; Barriuso, Jorge; Castellano, Daniel; Medina, Javier; López, Carlos; Segura, Ángel; Carrera, Sergio; Crespo, Guillermo; Fuster, José; Munarriz, Javier; García Alfonso, Pilar (BioMed Central, 2015-07-04)[Abstract] Background. Based on the mechanism of action, combining somatostatin analogues (SSAs) with mTOR inhibitors or antiangiogenic agents may provide synergistic effects for the treatment of patients with neuroendocrine ... -
Origin of renal cell carcinomas
Valladares-Ayerbes, Manuel; Aparicio Gallego, Guadalupe; Díaz-Prado, Silvia; Jiménez-Fonseca, Paula; García Campelo, Rosario; Antón-Aparicio, Luis M. (Springer, 2008-11-28)[Abstract] Cancer is a heritable disorder of somatic cells: environment and heredity are both important in the carcinogenic process. The primal force is the “two hits” of Knudson’s hypothesis, which has proved true for ...