Listar por autor "Hernández-García, Marta"
Mostrando ítems 1-4 de 4
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Deciphering mechanisms affecting cefepime-taniborbactam in vitro activity in carbapenemase-producing Enterobacterales and carbapenem-resistant Pseudomonas spp. isolates recovered during a surveillance study in Spain
Hernández-García, Marta; García-Castillo, María; Nieto-Torres, Marta; Bou, Germán; Ocampo-Sosa, Alain; Pitart, Cristina; Gracia-Ahufinger, Irene; Mulet, Xavier; Pascual, Álvaro; Tormo, Nuria; Oliver, Antonio; Ruiz-Garbajosa, Patricia; Cantón, Rafael (Springer Nature, 2023-12-02)[Abstract] Purpose: To characterize the resistance mechanisms affecting the cefepime-taniborbactam combination in a collection of carbapenemase-producing Enterobacterales (CPE) and carbapenem-resistant Pseudomonas spp. ... -
Imipenem-relebactam susceptibility in enterobacterales isolates recovered from ICU patients from Spain and Portugal (SUPERIOR and STEP studies)
Hernández-García, Marta; García-Castillo, María; Bou, Germán; Cercenado, Emilia; Delgado-Valverde, Mercedes; Oliver, Antonio; Pitart, Cristina; Rodríguez-Lozano, Jesús; Tormo, Nuria; Melo-Cristino, José; Pinto, Margarida Feijó; Gonçalves, Elsa; Alves, Valquíria; Vieira, Ana Raquel; Ramalheira, Elmano; Sancho, Luísa; Diogo, José; Ferreira, Rui; Cruz, Hugo; Chaves, Catarina; Duarte, Joana; Pássaro, Leonor; Díaz-Regañón, Jazmín; Cantón, Rafael (American Society of Microbiology, 2022-08-31)[Abstract] Imipenem-relebactam is a novel β-lactam-β-lactamase inhibitor combination. We evaluated the in vitro activity of imipenem-relebactam and comparators against Enterobacterales clinical isolates recovered in 8 ... -
Unravelling the mechanisms causing murepavadin resistance in Pseudomonas aeruginosa: lipopolysaccharide alterations and its consequences
Hernández-García, Marta; Barbero-Herranz, Raquel; Bastón-Paz, Natalia; Díez-Aguilar, María; López-Collazo, Eduardo; Márquez-Garrido, Francesc J.; Hernández-Pérez, José María; Baquero, Fernando; Ekkelenkamp, Miquel B.; Fluit, Ad C.; Fuentes-Valverde, Víctor; Moscoso, Miriam; Bou, Germán; del Campo, Rosa; Cantón, Rafael; Avendaño-Ortiz, José (Frontiers Media, 2024-12-06)[Abstract] Introduction: Murepavadin is an antimicrobial peptide (AMP) in clinical development that selectively targets Pseudomonas aeruginosa LptD and whose resistance profile remains unknown. We aimed to explore genomic ... -
WGS characterization of MDR Enterobacterales with different ceftolozane/tazobactam susceptibility profiles during the SUPERIOR surveillance study in Spain
Hernández-García, Marta; García-Fernández, Sergio; García-Castillo, María; Bou, Germán; Cercenado, Emilia; Delgado-Valverde, Mercedes; Mulet, Xavier; Pitart, Cristina; Rodríguez-Lozano, Jesús; Tormo, Nuria; López-Mendoza, Diego; Díaz-Ragañón, Jazmín; Cantón, Rafael (Oxford University Press on behalf of the Endocrine Society, 2020-10-22)[Abstract] Objectives: To analyse by WGS the ceftolozane/tazobactam (C/T) resistance mechanisms in Escherichia coli and Klebsiella spp. isolates recovered from complicated intra-abdominal and urinary tract infections in ...
