Barriada, José LuisGarcía, Marcos D.Peinador, CarlosNeira, IagoDomarco, OlayaFranchi, PaolaLucarini, Marco2026-01-072026-01-072020-06-22NEIRA, Iago, et al. An electrochemically controlled supramolecular zip tie based on host–guest chemistry of CB [8]. Organic & Biomolecular Chemistry, 2020, vol. 18, no 27, p. 5228-5233.1477-0539https://hdl.handle.net/2183/46722This is an accepted version of the published document. This version of the article has been accepted for publication, after peer review, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections.[Abstract] Three molecular threads incorporating two viologen units attached by an oligo-ethylene glycol chain of variable length and an electron rich naphthalene moiety were prepared. The internal viologen unit is connected to the naphthalene by a rigid linker that prevents the simultaneous complexation of these systems. The axle with the shortest chain (14+) in the presence of CB[8] placed the chain inside the macrocycle in aqueous media. In contrast, the longer chains in 24+ and 34+ allow locating the terminal viologen and the electron rich unit inside the cavity. Upon reduction of the bipyridinium salts, the system behaves like a zip tie relaxing the chain as a consequence of the insertion of both radical cation moieties within the CB[8] and making these switches as potential components for molecular machinery.engjournal articleopen access10.1039/D0OB01085E