Martín-Revuelta, SamuelFernández-Lozano, CarlosLiñares Blanco, José2026-09-032026-09-032025S. Martín Revuelta, C. Fernández-Lozano, and J. Liñares-Blanco, "In Silico Identification of Common Pre-existing Resistance Mechanisms to EGFR Inhibitors in Colorectal Cancer" [poster], Annual Congress of the European Association for Cancer Research (EACR 2025), 16–19 June 2025, Lisboa, Portugalhttps://hdl.handle.net/2183/49142Póster presentado en: Annual Congress of the European Association for Cancer Research (EACR 2025), 16–19 June 2025, Lisboa, Portugal. Abstract dispoñible en: https://hdl.handle.net/2183/49141.[Abstract]: This study presents an in silico multi-omic approach combining Non-Negative Matrix Factorization (NMF) and a drug enrichment score to identify pre-existing, shared transcriptomic latent factors driving resistance to EGFR inhibitors in colorectal cancer.eng© 2025Colorectal cancerEGFR inhibitorsNon-negative matrix factorizationconference outputopen access