Cayo, RodrigoMerino Carballeira, MaríaRuiz del Castillo, BelénCano, María E.García Calvo-Montes, JorgeBou, GermánMartínez-Martínez, Luis2026-09-232026-09-232014-07-15Cayô R, Merino M, Ruiz Del Castillo B, Cano ME, Calvo J, Bou G, Martínez-Martínez L. OXA-207, a novel OXA-24 variant with reduced catalytic efficiency against carbapenems in Acinetobacter pittii from Spain. Antimicrob Agents Chemother. 2014 Aug;58(8):4944-8.1098-6596https://hdl.handle.net/2183/49395Brief report[Abstract] A carbapenem-resistant Acinetobacter pittii strain carrying an OXA-24-like enzyme was isolated in northern Spain in 2008. Sequence analysis confirmed the presence of the novel bla(OXA-207) gene flanked by the site-specific XerC/XerD-like recombination binding sites and showing a unique Gly222Val substitution compared to OXA-24. Cloning and kinetic analysis showed that OXA-207 presents a reduction in the catalytic efficiency against carbapenems and a noticeable increase for oxacillin.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AcinetobacterAnti-Bacterial AgentsCarbapenemsOxacillinbeta-Lactamasesjournal articleopen access10.1128/AAC.02633-13