Tamayo, MaríaPértega-Díaz, SoniaMosquera Rey, AlejandroRodríguez, MontserratBlanco García, Francisco JFernández-Sueiro, José LuisGosálvez, JaimeFernández, José Luis2026-09-222026-09-222014-04-24Tamayo M, Pértega S, Mosquera A, Rodríguez M, Blanco FJ, Fernández-Sueiro JL, Gosálvez J, Fernández JL. Individual telomere length decay in patients with spondyloarthritis. Mutat Res. 2014 Jul;765:1-5.0921-8262https://hdl.handle.net/2183/49354Clinical trial[Abstract] Telomere length was sequentially determined in peripheral blood leukocytes (PBL) from patients with ankylosing spondylitis (AS; n = 44) and psoriatic arthritis (PsA; n = 42) followed through 2.93 ± 0.99 years, using a quantitative PCR (qPCR) assay. The initial telomere size from PsA patients was higher than those with cutaneous psoriasis only (n = 53), possibly due to the inflammatory condition. The qPCR assay was sensitive enough to evidence a significant telomere length shortening in PBL from practically all subjects and PsA patients showed a higher rate of loss of telomere sequence than patients with AS during the follow-up time.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Ankylosing spondylitisPsoriasisPsoriatic arthritisTelomere lengthqPCRjournal articleopen access10.1016/J.MRFMMM.2014.04.006