Orosa García, MiguelFranqueira, DoloresCid, ÁngelesAbalde, Julio2016-07-282016-07-282001-03Orosa, M., Franqueira, D., Cid, A. et al. Biotechnology Letters (2001) 23: 373. doi:10.1023/A:10056240052290141-5492http://hdl.handle.net/2183/17141The microalga Haematococcus pluvialis was cultured with NaNO3 from 0 to 1 g l−1 and optimal growth was obtained at 0.15 g l−1. Sodium acetate and malonate (from 0 to 2% w/v) enhanced the accumulation of astaxanthin three and five times higher, respectively, than in autotrophic control cultures. However, high concentration of those compounds strongly inhibited growth. The ratio chlorophyll a/total carotenoids was a good indicator of the extent of nitrogen deficiency in the cells.engThe final publication is available at Springer via http://dx.doi.org/10.1023/A:1005624005229AstaxanthinCanthaxanthinEchinenoneHaematococcus pluvialisPigmentsSecondary carotenoidsjournal articleopen access