García-Porta, JoanGalán, Pedro2019-10-112019-10-112019-09-091. Garcia-Porta, J. et al. Environmental temperatures shape thermal physiology as well as diversification and genome-wide substitution rates in lizards. Nat. Commun. 10, 4077 (2019).2041-1723http://hdl.handle.net/2183/24093[Abstract] Climatic conditions changing over time and space shape the evolution of organisms at multiple levels, including temperate lizards in the family Lacertidae. Here we reconstruct a dated phylogenetic tree of 262 lacertid species based on a supermatrix relying on novel phylogenomic datasets and fossil calibrations. Diversification of lacertids was accompanied by an increasing disparity among occupied bioclimatic niches, especially in the last 10 Ma, during a period of progressive global cooling. Temperate species also underwent a genome-wide slowdown in molecular substitution rates compared to tropical and desert-adapted lacertids. Evaporative water loss and preferred temperature are correlated with bioclimatic parameters, indicating physiological adaptations to climate. Tropical, but also some populations of cool-adapted species experience maximum temperatures close to their preferred temperatures. We hypothesize these species-specific physiological preferences may constitute a handicap to prevail under rapid global warming, and contribute to explaining local lizard extinctions in cool and humid climates.engAtribución 3.0 Españahttp://creativecommons.org/licenses/by/3.0/es/Climate-change ecologyConservation biologyHerpetologyPhylogeneticsjournal articleopen access