Marcos-Pérez, DiegoSánchez-Flores, MaríaMaseda, AnaLorenzo-López, LauraMillán-Calenti, José CarlosStrasser, BarbaraGostner, JohannaFuchs, DietmarPásaro, EduardoValdiglesias, VanessaLaffon, Blanca2018-01-152017-08-08Marcos-Pérez D, Sánchez-Flores M, Maseda A, Lorenzo-López L, Millán-Calenti JC, Strasser B, Gostner JM, Fuchs D, Pásaro E, Valdiglesias V, Laffon B. Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways. J Am Med Dir Assoc. 2017 Dec 1;18(12):1049-1057.1525-86101538-9375http://hdl.handle.net/2183/19988Original studyspaCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC-BY 4.0)http://creativecommons.org/licenses/by-nc-nd/4.0/FrailtyImmune activationKynurenine/tryptophan ratio neopterinNitritePhenylalanine/tyrosine ratioFrailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathwaysjournal articleopen access