González Montoro, Aldana MaríaCao, RicardoEspinosa, NelsonCudeiro, JavierMariño Alfonso, Xurxo2015-06-082015-04-14González-Montoro AM, Cao R, Espinosa N, Cudeiro J, Mariño J. Bootstrap testing for cross-correlation under low firing activity. J Comput Neurosci. 2015;38:577-587http://hdl.handle.net/2183/14639[Abstract] A new cross-correlation synchrony index for neural activity is proposed. The index is based on the integration of the kernel estimation of the cross-correlation function. It is used to test for the dynamic synchronization levels of spontaneous neural activity under two induced brain states: sleep-like and awake-like. Two bootstrap resampling plans are proposed to approximate the distribution of the test statistics. The results of the first bootstrap method indicate that it is useful to discern significant differences in the synchronization dynamics of brain states characterized by a neural activity with low firing rate. The second bootstrap method is useful to unveil subtle differences in the synchronization levels of the awake-like state, depending on the activation pathway.engThe final publication is avaliable at link.springer.comHypothesis testingSleep-wakeSpontaneous activitySynchronizationTonic activityjournal articleopen access