Mora-Boga, RubénVázquez-Muíños, OlallaPértega-Díaz, SoniaSalvador-De la Barrera, SebastianFerreiro-Velasco, María ElenaRodríguez Sotillo, AntonioMeijide-Faílde, RosaMontoto Marqués, Antonio2023-01-242022-11-28Mora-Boga R, Vázquez-Muíños O, Pértega-Díaz S, Salvador-de la Barrera S, Ferreiro-Velasco ME, Rodríguez-Sotillo A, Meijide-Failde RM, Montoto-Marqués A. Evaluation of the prognostic value of extra-parenchymal changes in traumatic spinal cord injury, assessed by magnetic resonance imaging. J Spinal Cord Med. 2024 Jul;47(4):540-548.1079-0268http://hdl.handle.net/2183/32383[Abstract] Objectives: To analyze the relationship between neurological progression following traumatic spinal cord injury and Spinal Cord Compression (SCC) and Spinal Ligamentous Injury (LI) by magnetic resonance imaging. Design: Retrospective observational study. Setting: Spinal Cord Injury Unit (A Coruña, Spain). Participants: Patients were admitted for traumatic spinal cord injury between January 2010 and December 2018 with a magnetic resonance imaging examination performed during the acute phase. Intervention: Evaluation of SCC and LI by magnetic resonance imaging. Outcome measures: Comparisons between neurological examination at admission and discharge were made, assessing ASIA Impairment Scale (AIS) grade and motor score. Results: Data from 296 patients were collected. A relationship between SCC and LI and complete injuries were found (P < 0.001). Improvement of the AIS grade was observed in 31.6% of patients with SCC and 31.3% with LI versus 42.7% and 37.8% of subjects without these complications, respectively. Regarding motor score, patients with SCC had lower mean values at the beginning (46.9 ± 26.8 versus 61.1 ± 29.9 in the control group, P < 0.001), as well as less improvement when assessed by the percentage of change (35.1 ± 37.5% versus 49.4 ± 38.1% in the control group, P = 0.010). Similar results were obtained in cases with LI: mean motor score at admission was 45.9 ± 26.7 versus 54.9 ± 29.4 in the control group (P = 0.014) and the percentage of change was 28.5 ± 37.1% in comparison to 46.0 ± 37.5% (P = 0.001) in the controls. Conclusions: There is a relationship between SCC and LI and complete spinal cord injury. This patient population has lower possibilities of improving their AIS grade and motor score.engCreative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC-BY-NC-ND 4.0)This is an Accepted Manuscript version of the following article, accepted for publication in The Journal of Spinal Cord Medicine.http://creativecommons.org/licenses/by-nc-nd/4.0/Magnetic resonance imagingPrognosisSpinal cord compressionTraumatic spinal cord injuryjournal articleopen access