Barge-Caballero, EduardoAlmenar-Bonet, LuisGonzález-Vílchez, FranciscoLambert Rodríguez, José LuisGonzález-Costello, JoséSegovia Cubero, JavierCastel-Lavilla, María A.Delgado Jiménez, Juan FranciscoGarrido-Bravo, Iris P.Rangel Sousa, DiegoMartínez-Sellés, ManuelDe la Fuente-Galán, LuisRábago Juan-Aracil, GregorioSanz-Julve, MarisaHervás-Sotomayor, DanielaMirabet, SoniaMuñiz, JavierCrespo-Leiro, María Generosa2026-04-142026-04-142017-09-26Barge-Caballero E, Almenar-Bonet L, Gonzalez-Vilchez F, Lambert-Rodríguez JL, González-Costello J, Segovia-Cubero J, Castel-Lavilla MA, Delgado-Jiménez J, Garrido-Bravo IP, Rangel-Sousa D, Martínez-Sellés M, De la Fuente-Galan L, Rábago-Juan-Aracil G, Sanz-Julve M, Hervás-Sotomayor D, Mirabet-Pérez S, Muñiz J, Crespo-Leiro MG. Clinical outcomes of temporary mechanical circulatory support as a direct bridge to heart transplantation: a nationwide Spanish registry. Eur J Heart Fail. 2018 Jan;20(1):178-186.1879-0844https://hdl.handle.net/2183/47970Multicenter study[Abstract] Background: In Spain, listing for high-urgent heart transplantation is allowed for critically ill candidates not weanable from temporary mechanical circulatory support (T-MCS). We sought to analyse the clinical outcomes of this strategy. Methods and results: We conducted a case-by-case, retrospective review of clinical records of 291 adult patients listed for high-urgent heart transplantation under temporary devices from 2010 to 2015 in 16 Spanish institutions. Survival after listing and adverse clinical events were studied. At the time of listing, 169 (58%) patients were supported on veno-arterial extracorporeal membrane oxygenation (VA-ECMO), 70 (24%) on temporary left ventricular assist devices (T-LVAD) and 52 (18%) on temporary biventricular assist devices (T-BiVAD). Seven patients transitioned from VA-ECMO to temporary ventricular assist devices while on the waiting list. Mean time on T-MCS was 13.1 ± 12.6 days. Mean time from listing to transplantation was 7.6 ± 8.5 days. Overall, 230 (79%) patients were transplanted and 54 (18.6%) died during MCS. In-hospital postoperative mortality after transplantation was 33.3%, 11.9% and 26.2% for patients bridged on VA-ECMO, T-LVAD and T-BiVAD, respectively (P = 0.008). Overall survival from listing to hospital discharge was 54.4%, 78.6% and 55.8%, respectively (P = 0.002). T-LVAD support was independently associated with a lower risk of death over the first year after listing (hazard ratio 0.52, 95% confidence interval 0.30-0.92). Patients treated with VA-ECMO showed the highest incidence rate of adverse clinical events associated with T-MCS. Conclusion: Temporary devices may be used to bridge critically ill candidates directly to heart transplantation in a setting of short waiting list times, as is the case of Spain. In our series, bridging with T-LVAD was associated with more favourable outcomes than bridging with T-BiVAD or VA-ECMO.engExtracorporeal membrane oxygenationHeart transplantationMechanical circulatory supportVentricular assist devicejournal articleopen access10.1002/EJHF.956